Active nickel-based reduction of organic compounds
Active nickel-based reduction of organic compounds
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DOI：
10.1023/b:rucb.0000019874.01782.b4
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发表时间：
2003-12-01
影响因子：
1.7
通讯作者：
Yus, M
中科院分区：
文献类型：
--
作者：
Alonso, F;Radivoy, G;Yus, M
还原体系NiCl2 （.）2H(2) o - li -芳烃（cat） （cat是催化剂）被提议用于还原广泛的有机化合物，包括烯烃、炔、羰基化合物、亚胺、卤化衍生物、磺酸盐、芳香族化合物、肼、偶氮和偶氮氧化合物、n -氧化物和硝基化合物。对于某些底物，还原程度是可以控制的。氘可以用氘水氯化镍加入到反应产物中。在不含镍盐的li -芳烃（cat）体系中，硝基酮、n -烷氧酰胺和酰基叠氮化物也被还原。
The reducing system NiCl2 (.) 2H(2)O-Li-arene(cat) (cat is catalyst) was proposed for use to reduce a wide range of organic compounds, including alkenes, alkynes, carbonyl compounds, imines, halogenated derivatives, sulfonates, aromatic compounds, hydrazines, azo and azoxy compounds, N-oxides, and nitrones. The degree of reduction can be controlled for some substrates. Deuterium can be incorporated in the reaction products using nickel chloride deuteriohydrate. Nitrones, N-alkoxyamides, and acyl azides are also reduced with the Li-arene(cat) system containing no nickel salt.