Visual object agnosia and pure word alexia: correlation of functional magnetic resonance imaging and lesion localization.

Visual object agnosia and pure word alexia: correlation of functional magnetic resonance imaging and lesion localization.
复制标题

视觉物体失认症和纯词失读症:功能磁共振成像与病变定位的相关性。

DOI:
10.1097/00004728-200401000-00010
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发表时间:
2004
影响因子:
1.3
通讯作者:
Prost,RobertW
Prost,RobertW
中科院分区:
医学4区
文献类型:
--
作者:
Salvan,CarmenV;Ulmer,JohnL;DeYoe,EdgarA;Wascher,Thomas;Mathews,VincentP;Lewis,JamesW;Prost,RobertW

文献摘要

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We present a case of a 64-year-old, right-handed female with a metastatic breast cancer lesion involving the left posterior inferior temporal lobe causing complete loss of the ability to recognize visually common objects and words. After her symptoms resolved on corticosteroid therapy, functional magnetic resonance imaging (fMRI) mapping demonstrated strong left-hemispheric dominance for word recognition and right-hemispheric dominance for object recognition. The case illustrates the relationships among ventral occipito-temporal cortical activation, lesion localization, and lesion-induced deficits of higher visual function. The relationship between hemispheric dominance determined by fMRI and risk of postoperative deficit depends on the specific visual function of interest.