CT-DETERMINED PULMONARY-ARTERY DIAMETERS IN PREDICTING PULMONARY-HYPERTENSION
CT-DETERMINED PULMONARY-ARTERY DIAMETERS IN PREDICTING PULMONARY-HYPERTENSION
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DOI：
10.1097/00004424-198401000-00005
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发表时间：
1984-01-01
影响因子：
6.7
通讯作者：
BRUNDAGE, BH
中科院分区：
文献类型：
--
作者：
KURIYAMA, K;GAMSU, G;BRUNDAGE, BH
探讨CT测量的肺动脉直径是否可作为肺动脉高压的指标，并作为计算平均肺动脉压的可靠依据。对32例心肺疾病患者和26例年龄和性别匹配的对照组进行CT扫描，测量主肺动脉、左肺动脉、右肺动脉近端、右肺动脉远端、叶间肺动脉和左肺动脉降支的直径。使用特殊的计算机程序测量直径，该程序可以显示动脉及其邻近组织的CT密度分布。主肺动脉正常直径的上限为28.6 mm（平均值+2 SD）。在患者组中，直径与心导管检查数据相关。在这些患者中，主肺动脉直径大于28.6 mm容易预测肺动脉高压的存在。主动脉和叶间肺动脉的横截面积（以体表面积[BAS]标准化）的计算值被认为是平均肺动脉压的最佳估计值（r = 0.89，P < 0.001和r = 0.66，P < 0.001）。多元回归分析给出了有用的方程：平均肺动脉压= -10.92 +0.07646 ×主肺动脉面积/BSA + 0.08084 ×右叶间肺动脉面积/BSA（r = 0.93，P < 0.0001）。由于CT可以精确、无创地测量肺动脉直径，因此它在检测肺动脉高压和估计平均肺动脉压方面具有价值。
Whether diameters of pulmonary arteries measured from computed tomographic (CT) scans could be used as indicators of pulmonary artery hypertension, and as a reliable base for calculating mean pulmonary artery pressure were determined. The diameters of the main, left, proximal right, distal right, interlobar and left descending pulmonary arteries were measured from CT scans in 32 patients with cardiopulmonary disease and in 26 age- and sex-matched control subjects. Diameters were measured using a special computer program that could display a CT density profile of the artery and its adjacent tissues. The upper limit of normal diameter for the main pulmonary artery was found to be 28.6 mm (mean + 2 SD). In the patient group, the diameters were correlated with data from cardiac catheterization. In these patients, a diameter of the main pulmonary artery above 28.6 mm readily predicted the presence of pulmonary hypertension. The calculated cross-sectional areas of the main and interlobar pulmonary arteries (normalized for body surface area [BAS]) were found to give the best estimates of mean pulmonary artery pressure (r = 0.89, P < 0.001 and r = 0.66, P < 0.001). Multiple regression analysis gave the useful equation: mean pulmonary artery pressure = -10.92 + 0.07646 .times. area of main pulmonary artery/BSA + 0.08084 .times. area of the right interlobar pulmonary artery/BSA (r = 0.93, P < 0.0001). Because CT allows precise, noninvasive measurement of the diameter of pulmonary arteries, it can be of value in detecting pulmonary hypertension and estimating mean pulmonary artery pressure.