Association of peak atrial longitudinal strain with atrial fibrillation recurrence in patients with chronic lung diseases following radiofrequency ablation
Association of peak atrial longitudinal strain with atrial fibrillation recurrence in patients with chronic lung diseases following radiofrequency ablation
复制标题
慢性肺病患者射频消融后峰值心房纵向应变与心房颤动复发的关系
DOI：
10.1111/imj.13768
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发表时间：
2018-07-01
影响因子：
2.1
通讯作者：
Ma, Chang-Sheng
中科院分区：
文献类型：
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作者：
Bai, Ying;Zhao, Ying;Ma, Chang-Sheng
背景：应变与射频消融（RFA）后房颤（AF）复发有关，但房颤合并慢性肺部疾病（CLD）的数据很少。目的：本研究旨在利用斑点跟踪超声心动图评估基线心房功能与房颤复发的关系。方法：对2013 ~ 2014年行RFA的87例CLD AF患者（平均年龄：61.91岁，男性：71.26%）的平均应变值（中位数：RFA前2 d）进行计算。在这些患者中，25例（28.74%）在平均10.3个月的随访期间出现房颤复发。结果：右心房纵向应变峰值（R-PALS）与左心房纵向应变峰值（L-PALS，标准化β = 0.45, P < 0.001）在多元线性回归中具有相关性。多因素Cox回归分析显示，R-PALS与冠心病AF复发相关（风险比0.86；95%可信区间（CI） 0.78 ~ 0.96, P = 0.005）。R-PALS患者>= 14.69%的房颤游离率高于R-PALS
Background: Strain was shown associated with atrial fibrillation (AF) recurrence after radiofrequency ablation (RFA), but data on AF patients complicated with chronic lung diseases (CLD) were rare.Aim: This study was designed to evaluate the relationship of baseline atrial function with AF recurrence in these patients using speckle-tracking echocardiography.Methods: Average strain values (median: 2 days before RFA) were calculated for 87 AF patients (Mean age: 61.91 years, male: 71.26%) with CLD undergoing RFA from 2013 to 2014. Of these patients, 25 (28.74%) experienced AF recurrence during a mean follow up of 10.3 months.Results: Peak right atrial longitudinal strain (R-PALS) was associated with peak left atrial longitudinal strain (L-PALS, Standardised beta = 0.45, P < 0.001) in multivariate linear regression. Multivariate Cox regression analysis showed R-PALS was associated with AF recurrence (hazard ratio, 0.86; 95% confidence interval (CI), 0.78-0.96, P = 0.005) in CLD. Patients with R-PALS >= 14.69% had higher AF free rate compared with R-PALS