Oral Polio Vaccine to Protect Against COVID-19: Out of the Box Strategies?
Oral Polio Vaccine to Protect Against COVID-19: Out of the Box Strategies?
复制标题
口服脊髓灰质炎疫苗以防止COVID-19：不开箱即用策略？
DOI：
10.1093/ofid/ofab367
复制
发表时间：
2021-08
影响因子：
4.2
通讯作者：
Mathur P
中科院分区：
文献类型：
--
作者：
Malave Sanchez M;Saleeb P;Kottilil S;Mathur P
2019年全球冠状病毒病大流行引发了人们对制定快速、广泛的战略以保护弱势群体并预防发病率和死亡率的重大关注。然而，即使采取积极的方法，控制大流行仍然具有挑战性，人们担心新出现的变种可能会逃脱疫苗，公众不遵守社交距离/预防措施，以及快速实施涉及大规模生产，分销和执行的全球疫苗接种计划的挑战。在这篇综述中，我们重新审视了减毒疫苗的使用，如口服脊髓灰质炎疫苗，这是安全的，易于管理，并可能提供对呼吸道病原体的交叉保护。我们讨论了支持其使用的理论基础和数据，并详细描述了可用于遏制大流行的可用疫苗。
The global coronavirus disease 2019 pandemic has raised significant concerns of developing rapid, broad strategies to protect the vulnerable population and prevent morbidity and mortality. However, even with an aggressive approach, controlling the pandemic has been challenging, with concerns of emerging variants that likely escape vaccines, nonadherence of social distancing/preventive measures by the public, and challenges in rapid implementation of a global vaccination program that involves mass production, distribution, and execution. In this review, we revisit the utilization of attenuated vaccinations, such as the oral polio vaccine, which are safe, easy to administer, and likely provide cross-protection against respiratory pathogens. We discuss the rationale and data supporting its use and detail description of available vaccines that could be repurposed for curtailing the pandemic.
登录
查看更多内容
影响因子：
4.5
作者：
Hansen JS;Thysen SM;Rodrigues A;Martins C;Fisker AB
通讯作者：
Fisker AB
DOI：
10.1126/science.abc6261
发表时间：
2020-09-04
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Arunachalam PS;Wimmers F;Mok CKP;Perera RAPM;Scott M;Hagan T;Sigal N;Feng Y;Bristow L;Tak-Yin Tsang O;Wagh D;Coller J;Pellegrini KL;Kazmin D;Alaaeddine G;Leung WS;Chan JMC;Chik TSH;Choi CYC;Huerta C;Paine McCullough M;Lv H;Anderson E;Edupuganti S;Upadhyay AA;Bosinger SE;Maecker HT;Khatri P;Rouphael N;Peiris M;Pulendran B
通讯作者：
Pulendran B
影响因子：
5.5
作者：
Garly, ML;Martins, CL;Aaby, P
通讯作者：
Aaby, P
DOI：
10.1073/pnas.2008410117
发表时间：
2020-07-28
影响因子：
11.1
作者：
Escobar, Luis E.;Molina-Cruz, Alvaro;Barillas-Mury, Carolina
通讯作者：
Barillas-Mury, Carolina
DOI：
10.1093/infdis/jiy320
发表时间：
2018-09-08
期刊：
The Journal of infectious diseases
影响因子：
--
作者：
Perciani CT;Sekhon M;Hundal S;Farah B;Ostrowski MA;Anzala AO;McKinnon LR;Jaoko W;MacDonald KS;Institute of Tropical and Infectious Diseases (UNITID) Group and the Kenyan AIDS Vaccine Initiative–Institute of Clinical Research (KAVI-ICR) Team
通讯作者：
Institute of Tropical and Infectious Diseases (UNITID) Group and the Kenyan AIDS Vaccine Initiative–Institute of Clinical Research (KAVI-ICR) Team