Validation of the 4P's Plus© screen for substance use in pregnancy validation of the 4P's Plus
Validation of the 4P's Plus© screen for substance use in pregnancy validation of the 4P's Plus
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DOI：
10.1038/sj.jp.7211823
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发表时间：
2007-12-01
影响因子：
2.9
通讯作者：
Bailey, L. K.
中科院分区：
文献类型：
--
作者：
Chasnoff, I. J.;Wells, A. M.;Bailey, L. K.
目的：本研究的目的是验证4P‘s Plus筛查孕期药物使用情况。研究设计：共228名登记参加产前检查的孕妇接受了4P’s Plus筛查，并接受了药物使用的随访临床评估。对4Ps Plus的信度、敏感度、特异度、阳性预测值和阴性预测值进行统计分析。结果：5个条目的总体信度为0.62。74名妇女(32.5%)筛查呈阳性。敏感度和特异度均很高，分别为87%和76%。阳性预测效度较低(36%)，但阴性预测效度较高(97%)。在31名临床评估为阳性的妇女中，45%的妇女每周使用药物少于1天。结论：4P‘s Plus可靠有效地筛查孕妇使用药物的风险，包括那些通常被其他围产期筛查方法遗漏的妇女。
Objective: The purpose of this study is to validate the 4P's Plus screen for substance use in pregnancy.Study Design: A total of 228 pregnant women enrolled in prenatal care underwent screening with the 4P's Plus and received a follow-up clinical assessment for substance use. Statistical analyses regarding reliability, sensitivity, specificity, and positive and negative predictive validity of the 4Ps Plus were conducted.Result: The overall reliability for the five-item measure was 0.62. Seventy-four ( 32.5%) of the women had a positive screen. Sensitivity and specificity were very good, at 87 and 76%, respectively. Positive predictive validity was low ( 36%), but negative predictive validity was quite high ( 97%). Of the 31 women who had a positive clinical assessment, 45% were using less than 1 day per week.Conclusion: The 4P's Plus reliably and effectively screens pregnant women for risk of substance use, including those women typically missed by other perinatal screening methodologies.