The α-specific cell identity factor Sxi1α is not required for virulence of Cryptococcus neoformans
The α-specific cell identity factor Sxi1α is not required for virulence of Cryptococcus neoformans
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DOI：
10.1128/iai.72.6.3643-3645.2004
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发表时间：
2004-06-01
影响因子：
3.1
通讯作者：
Heitman, J
中科院分区：
文献类型：
--
作者：
Hull, CM;Cox, GM;Heitman, J
新生隐球菌是一种人类真菌病原体，有两种交配型(a和α)。实验表明，在某些背景下，阿尔法菌株比a菌株的毒力更强。我们的研究表明，唯一已知的阿尔法特异因子SXI1pha对毒力来说并不是必需的。
Cryptococcus neoformans is a human fungal pathogen that has two mating types (a and alpha). Experiments have shown that in some backgrounds alpha strains are more virulent than a strains. Our studies reveal that the only known alpha-specific factor, SXI1alpha, is not necessary for virulence.