Nosocomial Clustering of NDM-1-Producing Klebsiella pneumoniae Sequence Type 340 Strains in Four Patients at a South Korean Tertiary Care Hospital

Nosocomial Clustering of NDM-1-Producing Klebsiella pneumoniae Sequence Type 340 Strains in Four Patients at a South Korean Tertiary Care Hospital
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DOI:
10.1128/jcm.06855-11
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发表时间:
2012-04-01
影响因子:
9.4
通讯作者:
Chong, Yunsop
Chong, Yunsop
中科院分区:
医学2区
文献类型:
--
作者:
Kim, Mi-Na;Yong, Dongeun;Chong, Yunsop

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2010年11月,在韩国首次从4名没有出国旅行史的患者中鉴定出产NDM-1肺炎克雷伯菌(NDMKP),这些患者在三级护理医院住院21至205天。所有的序列类型(ST)340和几乎相同的XbaI脉冲场凝胶电泳(PFGE)模式。携带bla(NDM-1)的质粒在IncN组中,大小范围为50至200 kb。这些发现表明,NDMKP已经被引入韩国之前,这种集群被发现。
In November 2010, NDM-1-producing Klebsiella pneumoniae (NDMKP) was identified for the first time in South Korea from four patients with no history of traveling abroad who stayed for 21 to 205 days in a tertiary care hospital. All were sequence type (ST) 340 and had nearly identical XbaI pulsed-field gel electrophoresis (PFGE) patterns. The bla(NDM-1)-carrying plasmids were in the IncN group, with sizes ranging from 50 to 200 kb. These findings suggest that NDMKP had already been introduced into South Korea before this clustering was found.