A new source of allergic contact dermatitis from UV‐cured (meth)acrylate adhesive
A new source of allergic contact dermatitis from UV‐cured (meth)acrylate adhesive
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紫外线固化（甲基）丙烯酸酯粘合剂是过敏性接触性皮炎的新来源
作者：
P. Calzavara;R. Capezzera;C. Zane;Andrea Brezzi;Giorgio Pasolini;Alessandro Ubiali;Fabio Facchetti
一名 68 岁男性出现全身性丘疹性皮疹，面部和手部水肿，发烧，间擦部位出现脓疱病，该症状是在开始使用 EuvanolA 鼻喷雾剂（植物提取物和苯扎氯铵）和 DolirhumA（扑热息痛和伪麻黄碱）治疗 1 天后开始出现的。 8 年前，他曾因类似的皮疹入院治疗，并伴有白细胞增多、嗜酸性粒细胞增多和活检显示浅表脓疱。诊断为急性全身性发疹性脓疱病，建议患者避免使用非甾体类抗炎药和内酰胺类抗生素药物，因为吡罗昔康和头孢曲嗪已出现皮疹。对于患者服用的第三种药物——鼻减充血剂（RhinalairA Ω 伪麻黄碱），没有提供此类建议。第二次出疹后 2 个月，用头孢曲嗪、吡罗昔康、扑热息痛、苯扎氯铵和伪麻黄碱进行斑贴试验。唯一的阳性检测是伪麻黄碱（10% pet.）（π π D2、π π D4）。
A 68-year-old man presented with a generalized papular eruption with oedema of the face and the hands, fever and pustulosis in intertriginous areas which had begun 1 day after starting treatment with EuvanolA nasal spray (plant extracts and benzalkonium chloride) and DolirhumA (paracetamol and pseudoephedrine). He has been hospitalized 8 years before for a similar eruption associated with hyperleucocytosis, eosinophilia and superficial pustules on biopsy. A diagnosis of acute generalized exanthematous pustulosis had been made and the patient advised to avoid nonsteroidal anti-inflammatory and blactam antibiotic drugs, because the eruption had appeared on piroxicam and cefatrizine. No such advice had been provided about a nasal decongestant (RhinalairA Ω pseudoephedrine), a 3rd drug that had been taken by the patient. Patch tests were performed 2 months after the 2nd eruption with cefatrizine, piroxicam, paracetamol, benzalkonium chloride and pseudoephedrine. The only positive test was to pseudoephedrine (10% pet.) (π π D2, π π D4).
DOI：
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发表时间：
1989
期刊：
Laboratory investigation; a journal of technical methods and pathology
影响因子：
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作者：
C. Compton;J. M. Gill;D. Bradford;S. Regauer;G. Gallico;Nicholas E. O'Connor
通讯作者：
C. Compton;J. M. Gill;D. Bradford;S. Regauer;G. Gallico;Nicholas E. O'Connor