Molecular neurobiology and pharmacology of the vasopressin oxytocin receptor family

Molecular neurobiology and pharmacology of the vasopressin oxytocin receptor family
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DOI:
10.1007/bf02071318
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发表时间:
1995-10-01
影响因子:
4
通讯作者:
Barberis, C
Barberis, C
中科院分区:
医学3区
文献类型:
--
作者:
Burbach, JPH;Adan, RAH;Barberis, C

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1. VP和OT通过4种受体亚型V-1a、V-1b、V-2和OT受体介导其丰富的效应.我们在这里回顾了VP/OT受体的药理学性质、结构活性关系、配体特异性的物种差异、表达模式和信号转导方面的最新见解。3.此外,还讨论了其他VP/OT受体亚型的存在。
1. VP and OT mediate their wealth of effects via 4 receptor subtypes V-1a, V-1b, V-2, and OT receptors.2. We here review recent insights in the pharmacological properties, structure activity relationships, species differences in ligand specificity, expression patterns, and signal transduction of VP/OT receptor.3. Furthermore, the existence of additional VP/OT receptor subtypes is discussed.