Daily functioning in glioma survivors: associations with cognitive function, psychological factors and quality of life.
Daily functioning in glioma survivors: associations with cognitive function, psychological factors and quality of life.
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了解和支持胶质瘤患者的生活质量（QoL）和日常功能是临床必需的。在这项研究中，我们研究了脑胶质瘤幸存者的认知、心理因素、健康相关生活质量测量和功能之间的关系。我们检查了23名胶质瘤幸存者的神经心理学、自我报告的认知、情绪和生活质量与工作和与工作无关的日常功能的相关性，并对最佳预测因子进行了线性模型。共有13/23的参与者在入组时正在工作。工作相关功能恶化的最佳模型（R2 = .83）包括自我报告的认知功能恶化、抑郁、孤独和脑肿瘤症状。与工作无关的功能恶化的最佳模型（R2 = .61）包括自我报告的认知功能、焦虑、睡眠障碍和身体功能恶化。神经心理学变量与功能的相关性并不高。较差的认知，特别是自我报告和社会心理结果可能损害神经胶质瘤幸存者的最佳功能。
Understanding and supporting quality of life (QoL) and daily functioning in glioma patients is a clinical imperative. In this study, we examined the relationship between cognition, psychological factors, measures of health-related QoL and functioning in glioma survivors. We examined neuropsychological, self-reported cognition, mood and QoL correlates of work and non-work-related daily functioning in 23 glioma survivors, and carried out linear models of the best predictors. A total of 13/23 participants were working at the time of enrollment. The best model for worse work-related functioning (R2 = .83) included worse self-reported cognitive function, depression, loneliness and brain tumor symptoms. The best model for worse non-work-related functioning (R2 = .61) included worse self-reported cognitive functioning, anxiety, sleep disturbance and physical functioning. Neuropsychological variables were not among the most highly correlated with function. Worse cognitive, particularly self-reported and psychosocial outcomes may compromise optimal functioning in glioma survivors.