A field trial to assess the effect of vaccination against feline herpesvirus, feline calicivirus and feline panleucopenia virus in 6-week-old kittens.
A field trial to assess the effect of vaccination against feline herpesvirus, feline calicivirus and feline panleucopenia virus in 6-week-old kittens.
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DOI：
10.1053/jfms.2000.0154
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发表时间：
2001-03-01
影响因子：
1.7
通讯作者：
Chalmers, W S
中科院分区：
文献类型：
--
作者：
Dawson, S;Willoughby, K;Chalmers, W S
在6、9和12周龄(早期计划)或9和12周龄(常规计划)使用三价(猫全白细胞减少症、猫疱疹病毒、猫杯状病毒)改良活疫苗，并评估接种的血清学反应。6周龄时母源抗体的水平也被确定。与未接种的小猫相比，在6周龄早期接种疫苗的小猫在9周龄时对每种病毒产生了相当大比例的抗体反应。在12周龄和15周龄时，常规免疫组和早期免疫组对任何抗原的抗体反应没有差异。
A trivalent (feline panleucopenia, feline herpesvirus, feline calicivirus), modified live, commercially available cat vaccine was used at either 6, 9 and 12 weeks of age (early schedule) or 9 and 12 weeks of age (conventional schedule), and the serological response to vaccination was assessed. The level of maternally derived antibody present at 6 weeks of age was also established. The use of early vaccination at 6 weeks of age induced an antibody response to each virus by 9 weeks of age in a significant proportion of kittens compared with unvaccinated littermates. There was no difference between the conventionally and early-vaccinated groups in terms of antibody response to any antigen by 12 and 15 weeks of age.