Optimal Protocol for Contrast-enhanced Free-running 5D Whole-heart Coronary MR Angiography at 3T
Optimal Protocol for Contrast-enhanced Free-running 5D Whole-heart Coronary MR Angiography at 3T
复制标题
DOI：
10.2463/mrms.tn.2022-0086
复制
发表时间：
2023-01-20
影响因子：
3
通讯作者：
Sakuma, Hajime
中科院分区：
文献类型：
--
作者：
Ishida, Masaki;Yerly, Jerome;Sakuma, Hajime
自由运行的5D全心冠状动脉磁共振血管成像(MRA)越来越受欢迎，因为它消除了对特定切片方向、呼吸门控或心脏触发的需要，从而降低了扫描的复杂性。在3T，梯度回波(GRE)序列最好与造影剂注射相结合。然而，对于3T GRE自由运行的5D全心冠状动脉MRA，无论是Gd造影剂的注射方案、RF激发角的选择，还是专用的图像重建参数都没有建立起来。在这项研究中，使用3T的GRE序列对Gd注入方案、用于有效脂肪抑制和连续数据采集的脂质不敏感二项式非共振射频激励(LIBRE)脉冲的RF激发角以及压缩传感重建正则化参数进行了优化，以用于增强自由运行的5D全心冠状动脉MRA。使用优化后的方案，在3T条件下，采用GRE序列对自由运行的5D全心冠状动脉MRA进行增强是可行的，且图像质量良好。
Free-running 5D whole-heart coronary MR angiography (MRA) is gaining in popularity because it reduces scanning complexity by removing the need for specific slice orientations, respiratory gating, or cardiac triggering. At 3T, a gradient echo (GRE) sequence is preferred in combination with contrast injection. However, neither the injection scheme of the gadolinium (Gd) contrast medium, the choice of the RF excitation angle, nor the dedicated image reconstruction parameters have been established for 3T GRE free-running 5D whole-heart coronary MRA. In this study, a Gd injection scheme, RF excitation angles of lipid-insensitive binominal off-resonance RF excitation (LIBRE) pulse for valid fat suppression and continuous data acquisition, and compressed-sensing reconstruction regularization parameters were optimized for contrast-enhanced free-running 5D whole-heart coronary MRA using a GRE sequence at 3T. Using this optimized protocol, contrast-enhanced free-running 5D whole-heart coronary MRA using a GRE sequence is feasible with good image quality at 3T.