PSYCHIATRIC RISK-FACTORS FOR ADOLESCENT SUICIDE - A CASE-CONTROL STUDY
PSYCHIATRIC RISK-FACTORS FOR ADOLESCENT SUICIDE - A CASE-CONTROL STUDY
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DOI：
10.1097/00004583-199305000-00006
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发表时间：
1993-05-01
影响因子：
13.3
通讯作者：
BAUGHER, M
中科院分区：
文献类型：
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作者：
BRENT, DA;PERPER, JA;BAUGHER, M
目的：本研究的目的是确定青少年自杀的精神危险因素。方法：将67名青少年自杀者与67名人口统计学匹配的社区对照进行比较。精神障碍的自杀受害者进行了评估，使用心理尸检协议和控制使用类似的半结构化精神访谈。风险因素通过比值比（OR）进行量化，也就是说，与对照组相比，自杀者中特定情况发生的相对频率。结果如下：与青少年自杀相关的最显著的精神菲斯克因素是重性抑郁（OR = 27.0）、双相混合状态（OR = 9.0）、物质滥用（OR = 8.5）和品行障碍（OR = 6.0）。物质滥用是一个更显着的危险因素时，共患情感性疾病比单独（OR = 17.0比3.3）。大多数抑郁自杀者患有原发性情感障碍（82%）。一个显着的少数（31%）抑郁症自杀者抑郁症少于3个月。既往自杀企图、自杀意念和杀人意念也与青少年自杀有关。结论：应高度重视为符合上述风险特征的青年开发有效的治疗方法。
Objective: The objective of this study was to determine the psychiatric risk factors for adolescent suicide. Method: Sixty-seven adolescent suicide victims were compared with 67 demographically matched community controls. Psychiatric disorder was assessed in suicide victims using a psychological autopsy protocol and in controls using similar semistructured psychiatric interviews. Risk factors were quantified by use of the odds ratio (OR), that is, the relative frequency of the occurrence of a given condition in the suicides compared with the controls. Results: The most significant psychiatric fisk factors associated with adolescent suicide were major depression (OR = 27.0), bipolar mixed state (OR = 9.0), substance abuse (OR = 8.5), and conduct disorder (OR = 6.0). Substance abuse was a more significant risk factor when comorbid with affective illness than when alone (OR = 17.0 versus 3.3). The majority of depressed suicide victims had a primary affective disorder (82%). A significant minority (31%) of depressed suicide victims had been depressed less than 3 months. Previous suicide attempts, suicidal ideation, and homicidal ideation also were associated with adolescent suicide. Conclusions: The development of effective treatments for youth who fit the above-noted risk profiles should be given high priority.