Stable early maternal report of behavioral inhibition predicts lifetime social anxiety disorder in adolescence.

Stable early maternal report of behavioral inhibition predicts lifetime social anxiety disorder in adolescence.
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DOI:
10.1097/chi.0b013e3181ae09df
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发表时间:
2009-09
影响因子:
13.3
通讯作者:
Fox NA
Fox NA
中科院分区:
医学1区
文献类型:
--
作者:
Chronis-Tuscano A;Degnan KA;Pine DS;Perez-Edgar K;Henderson HA;Diaz Y;Raggi VL;Fox NA

文献摘要

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行为抑制(BI)是儿童早期可识别的一种气质风格,被认为是焦虑症,特别是社交焦虑症(SAD)发展的危险因素。然而,很少有研究在多个发育时间点评估BI的稳定性,并跟踪参与者进入青春期——这是SAD发病风险最高的发育时期。目前的研究采用前瞻性纵向设计来确定稳定的早期BI是否预示着青少年精神疾病的存在和持续的社交焦虑水平。据推测,稳定的BI可以预测青少年精神病诊断的存在,特别是SAD。参与者包括126名14至16岁的青少年,他们在4个月大时首次从医院出生记录中招募。在14个月至7岁之间的多个时间点测量气质。在青春期,对父母和青少年进行了诊断性访谈,并收集了青少年和父母报告的社交焦虑的连续测量。稳定的母亲报告的早期BI与青春期终身SAD诊断的几率增加3.79倍相关,但与其他诊断无关(95%置信区间1.18-12.12)。稳定的母亲报告的早期BI也预测了青少年和父母对持续社交焦虑症状的独立评分。研究结果表明,稳定的母亲报告的早期BI可预测终生SAD,这对SAD的早期识别和预防具有重要意义。
Behavioral inhibition (BI), a temperamental style identifiable in early childhood, is considered a risk factor for the development of anxiety disorders, particularly social anxiety disorder (SAD). However, few studies examining this question have evaluated the stability of BI across multiple developmental time points and followed participants into adolescence—the developmental period during which risk for SAD onset is at its peak. The current study used a prospective longitudinal design to determine whether stable early BI predicted the presence of psychiatric disorders and continuous levels of social anxiety in adolescents. It was hypothesized that stable BI would predict the presence of adolescent psychiatric diagnoses, specifically SAD. Participants included 126 adolescents aged 14 to 16 years who were first recruited at 4 months of age from hospital birth records. Temperament was measured at multiple time points between the ages of 14 months and 7 years. In adolescence, diagnostic interviews were conducted with parents and adolescents, and continuous measures of adolescent- and parent-reported social anxiety were collected. Stable maternal-reported early BI was associated with 3.79 times increased odds of a lifetime SAD diagnosis, but not other diagnoses, during adolescence (95% confidence interval 1.18–12.12). Stable maternal-reported early BI also predicted independent adolescent and parent ratings of ongoing social anxiety symptoms. Findings suggesting that stable maternal-reported early BI predicts lifetime SAD have important implications for the early identification and prevention of SAD.