Physical and Biological Properties of a High-Plasticity Tricalcium Silicate Cement

Physical and Biological Properties of a High-Plasticity Tricalcium Silicate Cement
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DOI:
10.1155/2018/8063262
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发表时间:
2018-01-01
影响因子:
--
通讯作者:
Piva, Evandro
Piva, Evandro
中科院分区:
生物学3区
文献类型:
--
作者:
Galarca, Arthur Dias;de Oliveira Da Rosa, Wellington Luiz;Piva, Evandro

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介绍。矿物三氧化骨料(MTA)是一种三钙基硅酸盐、二钙硅酸盐基质。尽管MTA具有良好的生物学特性,但由于其砂状一致性,一些临床医生仍然声称在制备后处理MTA有困难。本研究的目的是比较MTA Repair HP (Angelus, Londrina, PR, Brazil)与MTA Angelus (Angelus, Londrina, PR, Brazil)的理化性质和细胞毒性。材料和方法。评估的性能包括粒径、凝固时间、流量、膜厚度、透光性、水溶性、抗压强度和细胞毒性。以p < 0.05为差异有统计学意义进行统计学分析。结果。在透光性、吸水性和溶解度方面,MTA Repair HP与MTA Angelus在统计学上相似。MTA Angelus膜厚值高于MTA Repair HP,差异有统计学意义(p < 0.05)。MTA Angelus 28 d抗压强度低于MTA Repair HP,差异有统计学意义(p < 0.05)。MTA修复HP设定更慢(p < 0.05)。相对于细胞活力,MTA Repair HP在24和48 h后的细胞活力与MTA Angelus具有统计学上的相似。结论。与MTA Angelus相比,MTA Repair HP在28天后具有相似的细胞活力、更低的膜厚度、更高的流量、凝固时间和抗压强度值。总的来说,MTA Repair HP具有与MTA Angelus相似的物理化学和生物特性。
Introduction. Mineral Trioxide Aggregate (MTA) is a tricalcium-based silicate, dicalcium silicate matrix. Despite its good biologic properties, some clinicians still claim to have difficulties in handling MTA after its preparation due to its sandy consistency. The aim of the present study was to evaluate the physicochemical properties and cytotoxicity of MTA Repair HP (Angelus, Londrina, PR, Brazil) compared with MTA Angelus (Angelus, Londrina, PR, Brazil). Materials and Method. The properties assessed were particle size, setting time, flow, film thickness, radiopacity, water solubility, compressive strength, and cytotoxicity. Statistical analysis was performed considering p < 0.05 as statistically significant. Results. For radiopacity, water absorption and solubility MTA Repair HP were statistically similar to MTA Angelus. The MTA Angelus had statistically different film thickness values, higher than MTA Repair HP (p < 0.05). Besides, MTA Angelus showed a lower and statistically different compressive strength after 28 days than MTA Repair HP (p < 0.05). Additionally, MTA Repair HP set more slowly (p < 0.05). Relative to cell viability, MTA Repair HP was statistically similar to MTA Angelus after 24 and 48 h in cell viability. Conclusions. The MTA Repair HP presented similar cell viability, lower film thickness, higher flow, setting time, and compressive strength values after 28 days than MTA Angelus. In general, the MTA Repair HP presented physicochemical and biological properties similar to the MTA Angelus.