Malaria in travelers: A review of the GeoSentinel surveillance network
Malaria in travelers: A review of the GeoSentinel surveillance network
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DOI：
10.1086/424510
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发表时间：
2004-10-15
影响因子：
11.8
通讯作者：
Torresi, J
中科院分区：
文献类型：
--
作者：
Leder, K;Black, J;Torresi, J
背景疟疾是一种常见的和重要的旅行感染。我们已经检查了报告给GeoSentinel监测网络的数据，以突出旅行者疟疾的特征。共报告了1 140例疟疾病例（60%的病例是恶性疟原虫引起的，24%是间日疟原虫引起的）。男性受试者占研究人群的69%。中位旅行持续时间为34天;然而，37%的受试者的旅行持续时间小于或等于4周。大多数旅行者在旅行前没有与医疗保健提供者接触。大多数病例发生在旅行者（39%）或移民/难民（38%）中。最常见的旅行原因是拜访朋友/亲戚（35%）或旅游（26%）。四分之三的感染发生在撒哈拉以南非洲。重症和/或并发症33例，死亡3例。与GeoSentinel数据库中的其他人相比，疟疾患者更经常前往撒哈拉以南非洲，更经常拜访朋友/亲戚，旅行时间更长，返回后更早出现，更有可能在就诊时发烧，旅行前遭遇的可能性更小。相反，移民和朋友或亲戚的访客，较高比例（73%）的传教士/志愿者组谁开发疟疾有一个旅行前遇到一个卫生保健提供者。到撒哈拉以南非洲和大洋洲旅行与获得疟疾的相对风险最大相关。我们已经使用了一个全球数据库，以确定与疟疾收购和患者类型，访问的目的地，旅行时间和疟疾物种收购的特点差异患者和旅行的特点。
Background. Malaria is a common and important infection in travelers.Methods. We have examined data reported to the GeoSentinel surveillance network to highlight characteristics of malaria in travelers.Results. A total of 1140 malaria cases were reported ( 60% of cases were due to Plasmodium falciparum, 24% were due to Plasmodium vivax). Male subjects constituted 69% of the study population. The median duration of travel was 34 days; however, 37% of subjects had a travel duration of less than or equal to4 weeks. The majority of travellers did not have a pretravel encounter with a health care provider. Most cases occurred in travelers (39%) or immigrants/refugees (38%). The most common reasons for travel were to visit friends/relatives (35%) or for tourism (26%). Three-quarters of infections were acquired in sub-Saharan Africa. Severe and/or complicated malaria occurred in 33 cases, with 3 deaths. Compared with others in the GeoSentinel database, patients with malaria had traveled to sub-Saharan Africa more often, were more commonly visiting friends/relatives, had traveled for longer periods, presented sooner after return, were more likely to have a fever at presentation, and were less likely to have had a pretravel encounter. In contrast to immigrants and visitors of friends or relatives, a higher proportion (73%) of the missionary/volunteer group who developed malaria had a pretravel encounter with a health care provider. Travel to sub-Saharan Africa and Oceania was associated with the greatest relative risk of acquiring malaria.Conclusions. We have used a global database to identify patient and travel characteristics associated with malaria acquisition and characterized differences in patient type, destinations visited, travel duration, and malaria species acquired.