Systematic evaluation of natural phenolic antioxidants from 133 Indian medicinal plants
Systematic evaluation of natural phenolic antioxidants from 133 Indian medicinal plants
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DOI：
10.1016/j.foodchem.2006.06.033
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发表时间：
2007-01-01
期刊：
影响因子：
8.8
通讯作者：
Sun, Mei
中科院分区：
文献类型：
--
作者：
Surveswaran, Siddharthan;Cai, Yi-Zhong;Sun, Mei
采用ABTS、DPPH和FRAP测定法对来自64科的133种印度药用植物的总抗氧化能力进行了评估，并采用Folin-Ciocalteu测定法测定了它们的总酚含量。这些物种表现出广泛的抗氧化活性，从0.16至500.70 mmol TEAC/100 g DW的ABTS测定。抗氧化活性值类似地随着DPPH和FRAP测定而变化。总抗氧化能力与酚类物质含量呈显著的线性正相关（R = 0.89-0.97），说明酚类物质是供试药用植物的主要抗氧化成分。通过反相高效液相色谱法对83种选定药用植物的主要酚类化合物进行初步鉴定，发现有酚酸、单宁、黄酮类化合物、姜黄素、香豆素、木脂素和奎宁。诃子的果实，石榴果皮和漆树的五倍子表现出非常高水平的水解单宁，儿茶的树胶除了单宁外，还表现出非常高水平的儿茶素和表儿茶素。许多药用植物中的主要酚类化合物是第一次被鉴定出来的（例如，大戟、通花牵牛和胡黄连）。对大量印度药用植物的系统调查证明对于了解它们在阿育吠陀医学中的化学成分和功能非常重要，并有助于寻找有效抗氧化剂的天然来源。(c)2006爱思唯尔有限公司保留所有权利。
Total antioxidant capacities of 133 Indian medicinal plant species sampled from 64 families were assessed by ABTS, DPPH and FRAP assays, and their total phenolic contents measured by Folin-Ciocalteu assay. These species exhibited a broad range of antioxidant activities, varying from 0.16 to 500.70 mmol TEAC/100g DW in the ABTS assay. The antioxidant activity values similarly varied with the DPPH and FRAP assays. Significant and positive linear correlations were found between total antioxidant capacities and phenolic contents (R = 0.89-0.97), indicating that phenolics were the dominant antioxidant constituents in the tested medicinal plants. Preliminary identification of the major phenolic compounds from 83 selected medicinal plants by reversed-phase HPLC revealed phenolic acids, tannins, flavonoids, curcuminoids, coumarins, lignans, and quinines. The fruit of Terminalia chebula, pericarp of Punica granatum and gall of Rhus succedanea showed very high levels of hydrolysable tannins, and the gum of Acacia catechu presented very high levels of catechin and epicatechin in addition to tannins. Major phenolics in many of the medicinal plants were identified for the first time (e.g., Euphorbia lathyrus, Ipomoea turpethum, and Picrorrhiza kurroa). This systematic investigation of a large number of Indian medicinal plants proved important for understanding their chemical constituents and functionality in Ayurvedic medicine, and contributes to the search for natural sources of potent antioxidants. (c) 2006 Elsevier Ltd. All rights reserved.