OXYGEN DESATURATION DURING SLEEP IN INFANTS AND YOUNG-CHILDREN WITH CONGENITAL HEART-DISEASE
OXYGEN DESATURATION DURING SLEEP IN INFANTS AND YOUNG-CHILDREN WITH CONGENITAL HEART-DISEASE
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DOI：
10.1016/s0022-3476(05)81193-x
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发表时间：
1992-08-01
影响因子：
5.1
通讯作者：
TEPPER, RS
中科院分区：
文献类型：
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作者：
HIATT, PW;MAHONY, L;TEPPER, RS
对19名6 +/- 4个月的先天性心脏病婴儿和11名8 +/- 5个月的正常婴儿进行睡眠时血氧饱和度（SaO 2）和肺功能评估，以确定先天性心脏病婴儿在睡眠时是否有更频繁的氧饱和度下降，如果有，其与潜在肺功能的关系。根据心导管检查时主动脉血氧饱和度（SaO_2）的变化，将先天性心脏病患儿分为无紫绀型（n = 11）和紫绀型（n = 8）。肺功能检查包括呼吸频率、功能残气量、呼吸系统总顺应性和功能残气量下的最大流量。在整个睡眠时间内，每个5分钟时段的最低SaO 2（SaO 2L）平均值存在显著差异（正常94% +/-2%，无紫绀90% +/-3%，紫绀74% +/- 4%; p
Oxygen saturation (SaO2) during sleep and pulmonary functions were evaluated in 19 infants with congenital heart disease, aged 6 +/- 4 months, and in 11 normal infants, aged 8 +/- 5 months, to determine whether infants with congenital heart disease have more frequent oxygen desaturation during sleep and, if so, its relationship to underlying pulmonary function. Infants with congenital heart disease were classified os acyanotic (n = 11) or cyanotic (n = 8) on the basis of their aortic SaO2 ai the time of cardiac catheterization (greater or less than 90% SaO2). Pulmonary function tests included respiratory rate, functional residual capacity, total respiratory system compliance, and maximal flows at functional residual capacity. Significant differences were found in the values for the lowest SaO2 of each 5-minute epoch (SaO2L) averaged during the entire sleep time (normal 94% +/- 2%, acyanotic 90% +/- 3%, and cyanotic 74% +/- 4%; p