Mimotope vaccines: epitope mimics induce anti-cancer antibodies.
Mimotope vaccines: epitope mimics induce anti-cancer antibodies.
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DOI:
10.1016/j.imlet.2007.07.008
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发表时间:
2007-10-31
影响因子:
4.4
通讯作者:
Jensen-Jarolim, Erika
中科院分区:
文献类型:
--
作者:
Riemer, Angelika B.;Jensen-Jarolim, Erika
Mimotopes are epitope-mimicking structures. When applied for immunizations they induce desired antibody specificities exclusively based on the principle of molecular mimicry. This is important as antibodies directed against tumor-associated antigens may harbor diverse biological effects depending on their epitope specificity. Thus they may inhibit or promote tumor growth. This review gives an update on different vaccination strategies based on the mimotope concept.
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发表时间:
1995-04-11
影响因子:
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