Arrested development: coordinating regeneration with development and growth in Drosophila melanogaster
Arrested development: coordinating regeneration with development and growth in Drosophila melanogaster
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DOI：
10.1016/j.gde.2016.06.008
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发表时间：
2016-10-01
影响因子：
4
通讯作者：
Halme, Adrian
中科院分区：
文献类型：
--
作者：
Jaszczak, Jacob S.;Halme, Adrian
The capacity for tissues to regenerate often varies during development. A better understanding how developmental context regulates regenerative capacity will be an important step towards enhancing the regenerative capacity of tissues to repair disease or damage. Recent work examining the regeneration of imaginal discs in the fruit fly, Drosophila melanogaster, has begun to identify mechanisms by which developmental progress restricts regeneration, and elucidate how Drosophila coordinates regenerative repair with the growth and development of the entire organism. Here we review recent advances in describing the interplay between development and tissue regeneration in Drosophila and identify questions that arise from these findings.
