The inclusion of minority groups in clinical trials: problems of under representation and under reporting of data.
The inclusion of minority groups in clinical trials: problems of under representation and under reporting of data.
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DOI：
10.1080/08989620490891412
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发表时间：
2004-07-01
期刊：
影响因子：
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通讯作者：
Gold, Jennifer
中科院分区：
文献类型：
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作者：
Rochon, Paula A;Mashari, Azad;Gold, Jennifer
目的：评估随机对照试验 (RCT) 中少数群体的代表性，以及报告此信息的频率。 研究设计：审稿人从 1999 年六种主要医学期刊上发表的所有 RCT 中收集研究样本的种族/民族构成数据。 结果：在 280 项 RCT 中，大多数（204 项，71.3%）没有提供有关参与者种族/民族的信息。在美国的 89 项随机对照试验中，有 50 项（56.1%）报告了其少数派分布。相对于其他试验，由美国国立卫生研究院 (NIH) 资助的试验 (n = 52) 更有可能报告种族/民族数据（55.8% vs. 23.7%；x2 = 20.9，p
OBJECTIVE: To evaluate the representation of minority groups in randomized control trials (RCTs), and the frequency with which this information is reported.STUDY DESIGN: Reviewers collected data on the racial/ethnic composition of study samples from all RCTs published in six leading medical journals in 1999.RESULTS: Of the 280 RCTs, most (204, 71.3%) provided no information on the race/ethnicity of participants. Of the 89 U.S.-based RCTs, 50 (56.1%) reported their minority distribution. Relative to other trials, those funded by the National Institute of Health (NIH) (n = 52) were more likely to report race/ethnicity data (55.8% vs. 23.7%; x2 = 20.9, p