Contraceptive methods and the risk of Chlamydia trachomatis infection in young women.
Contraceptive methods and the risk of Chlamydia trachomatis infection in young women.
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年轻女性的避孕方法和沙眼衣原体感染的风险。
DOI：
10.1093/oxfordjournals.aje.a117709
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发表时间：
1995
影响因子：
5
通讯作者：
Stamm,WE
中科院分区：
文献类型：
--
作者：
Park,BJ;Stergachis,A;Scholes,D;Heidrich,FE;Holmes,KK;Stamm,WE
为了评估避孕方法与宫颈沙眼衣原体感染之间的关系，作者研究了 1,779 名 15-34 岁非孕妇的人群样本，这些女性接受了细胞培养诊断测试以检测衣原体。沙眼是一个健康维护组织。屏障避孕法使用者被分类为在测试时报告使用以下方法之一的人：避孕套、隔膜、宫颈帽、杀精海绵、泡沫或阴道杀精栓剂。与同一年龄段的所有其他女性相比，屏障方法与 25 岁或以上女性衣原体感染风险降低相关（调整后的患病率比值比 = 0.15，95% 置信区间 (Cl) 0.04–0.66）。与仅未避孕的女性相比，调整后的患病率比值比为 0.34 (95% Cl 0.06–1.99)。对于 25 岁以下的女性，屏障方法的保护作用并不明显。使用任一参照组，口服避孕药的使用与沙眼衣原体感染的风险均无关。与所有其他女性相比，调整后的患病率优势比为 0.99 (95% Cl 0.57–1.73)，与未避孕女性相比，调整后的患病率优势比为 0.88 (95% Cl 0.44–1.79)。这些发现表明，目前屏障方法的使用模式因年龄而异，并且仅提供针对宫颈癌的选择性保护。沙眼感染。Am J Epidemiol 1995；142：771–8。
To evaluate the relation between contraceptive methods and cervicalChlamydia trachomatisinfection, the authors studied a population-based sample of 1,779 nonpregnant women aged 15–34 years who underwent cell culture diagnostic testing for the detection ofC. trachomatisat a health maintenance organization. Barrier contraceptive method users were classified as those who reported using one of the following methods at time of testing: condom, diaphragm, cervical cap, spermicidal sponge, foam, or vaginal spermicidal suppositories. Barrier methods were associated with a reduction in the risk of chlamydial infection in women aged 25 years or older when compared with all other women in the same age category (adjusted prevalence odds ratio = 0.15, 95% confidence interval (Cl) 0.04–0.66). When compared with only noncontracepting women, the adjusted prevalence odds ratio was 0.34 (95% Cl 0.06–1.99). The protective effect of barrier methods was not evident in women younger than age 25 years. Oral contraceptive use was not associated with the risk of C. trachomatis infection using either referent group; the adjusted prevalence odds ratio was 0.99 (95% Cl 0.57–1.73) compared with all other women, and 0.88 (95% Cl 0.44–1.79) compared with noncontracepting women. These findings suggest that present patterns of use of barrier methods differ by age and afford only selective protection against cervicalC. trachomatisinfections.Am J Epidemiol1995;142:771–8.