Practical thiol surrogates and protective groups for arylthiols for Suzuki-Miyaura conditions
Practical thiol surrogates and protective groups for arylthiols for Suzuki-Miyaura conditions
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DOI：
10.1021/jo052624z
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发表时间：
2006-03-03
影响因子：
3.6
通讯作者：
Mase, T
中科院分区：
文献类型：
--
作者：
Itoh, T;Mase, T
我们已经开发了实用的硫醇替代物和芳基硫醇保护基团的铃木-宫浦反应。2-乙基己基-3-巯基丙酸酯和4-（2 ′-巯基乙基）吡啶不仅是很好的巯基替代物，而且是很好的巯基保护基团。我们已经证明了这些保护基团在水性铃木-宫浦条件下的耐受性。
We have developed practical thiol surrogates and arylthiol protective groups for the Suzuki-Miyaura reaction. 2-Ethylhexyl-3-mercaptopropionate and 4-(2'-mercaptoethyl)pyridine were shown to be not only good thiol surrogates but also good protective groups for thiol. We have demonstrated toleration of these protective groups under aqueous Suzuki-Miyaura conditions.