A race between SARS-CoV-2 variants and vaccination: The case of the B.1.1.7 variant in France
A race between SARS-CoV-2 variants and vaccination: The case of the B.1.1.7 variant in France
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SARS-CoV-2 变种与疫苗接种之间的竞赛：法国 B.1.1.7 变种的案例
DOI：
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发表时间：
2021
期刊：
影响因子：
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通讯作者：
S. Cauchemez
中科院分区：
文献类型：
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作者：
Cécile Paolo Bosetti;T. Kiem;A. Andronico;J. Paireau;D. Bruhl;B. Lina;Y. Yazdanpanah;A. Fontanet;V. Colizza;P. Böelle;S. Cauchemez
SARS-CoV-2大流行在更易传播的变种的出现和疫苗的推出之间进入了一场不确定的竞赛。在这里，我们开发了一个数学模型，以法国大都市B.1.1.7变异体的崛起为案例，评估变异体、疫苗和非药物干预的相互作用可能如何影响大流行动态。我们的分析突出了SARS-CoV-2大流行管理面临的挑战，并表明需要向高危人群快速推出疫苗和非药物干预措施，以减轻新出现的变种的影响。
The SARS-CoV-2 pandemic has entered an uncertain race between the emergence of variants that are more transmissible and vaccine roll-out. Here, we developed a mathematical model to evaluate how the interplay of variants, vaccines and non-pharmaceutical interventions might shape the pandemic dynamics, using the rise of the B.1.1.7 variant in metropolitan France as a case study. Our analysis highlights the challenges ahead for the management of the SARS-CoV-2 pandemic and shows how the quick roll-out of vaccines to at-risk individuals and non-pharmaceutical interventions are needed to mitigate the impact of the emerging variants.