Immunodeficiency and Dysregulation: Report of the 2015 Workshop of the Society for Hematopathology/European Association for Haematopathology.
Immunodeficiency and Dysregulation: Report of the 2015 Workshop of the Society for Hematopathology/European Association for Haematopathology.
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免疫缺陷和失调：血液病理学会/欧洲血液病理学会 2015 年研讨会报告。
DOI：
10.1093/ajcp/aqw200
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发表时间：
2017
影响因子：
3.5
通讯作者：
Jaffe,ElaineS
中科院分区：
文献类型：
--
作者：
Natkunam,Yasodha;Gratzinger,Dita;deJong,Daphne;Chadburn,Amy;Goodlad,JohnR;Chan,JohnKC;Said,Jonathan;Jaffe,ElaineS
免疫缺陷相关淋巴组织增生性疾病 (LPD) 是一个异质性群体，范围从自限性增生到侵袭性淋巴瘤。这些 LPD 的临床病理学谱、致癌病毒的作用、治疗结果和潜在疾病机制尚不完全清楚。 2015 年免疫缺陷和失调研讨会由血液病理学协会 (SH) 和欧洲血液病理学协会 (EAHP) 组织，汇集了来自不同临床背景的大量注释明确的病例，包括来自 21 个国家的 415 例病例。这些案例提供了评估和比较各种免疫缺陷相关 LPD、评估该领域进展、建立在当前理解和分类方法基础上的机会，并探索未来研究的领域。
Immunodeficiency-related lymphoproliferative disorders (LPDs) form a heterogeneous group that ranges from selflimiting hyperplasias to aggressive lymphomas. The clinicopathologic spectrum, role of oncogenic viruses, treatment outcomes, and underlying disease mechanisms of these LPDs are incompletely understood. The 2015 Workshop on Immunodeficiency and Dysregulation, organized by the Society for Hematopathology (SH) and the European Association for Haematopathology (EAHP), brought together a large number of well-annotated cases from diverse clinical backgrounds and included 415 cases from 21 countries. These cases offered the opportunity to evaluate and compare a wide spectrum of immunodeficiency-related LPDs, assess progress in the field, build on the current understanding and approach to classification, and explore areas for future study.