Two putative c-type multiheme cytochromes required for the expression of OmcB, an outer membrane protein essential for optimal Fe(III) reduction in Geobacter sulfurreducens

Two putative c-type multiheme cytochromes required for the expression of OmcB, an outer membrane protein essential for optimal Fe(III) reduction in Geobacter sulfurreducens
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DOI:
10.1128/jb.188.8.3138-3142.2006
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发表时间:
2006-04-01
影响因子:
3.2
通讯作者:
Lovley, DR
Lovley, DR
中科院分区:
生物学3区
文献类型:
--
作者:
Kim, BC;Qian, XL;Lovley, DR

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两个同源的硫还原地杆菌c型细胞色素基因omcG和omcH的缺失,降低了铁(III)还原的速率,降低了铁(III)还原的关键外膜细胞色素OmcB的水平,而不影响其转录。两种基因的表达均恢复了Fe(III)还原和OmcB表达,表明功能相似。
Deletion of two homologous Geobacter sulfurreducens c-type cytochrome genes, omcG and omcH, decreased the rate of Fe(III) reduction and decreased the level of an outer membrane cytochrome critical for Fe(III) reduction, OmcB, without affecting its transcription. Expression of either gene restored Fe(III) reduction and OmcB expression, suggesting functional similarity.