Nitrogen Balance and Bioavailability of Amino Acids in Spirulina Diet-Fed Wistar Rats
Nitrogen Balance and Bioavailability of Amino Acids in Spirulina Diet-Fed Wistar Rats
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螺旋藻饮食喂养的 Wistar 大鼠的氮平衡和氨基酸生物利用度
DOI：
10.1021/acs.jafc.1c04840
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发表时间：
2021
影响因子：
6.1
通讯作者：
Miyoshi Noriyuki
中科院分区：
文献类型：
--
作者：
Shioji Yudai;Kobayashi Takuma;Yoshida Takuya;Otagiri Tomoka;Onoda Keita;Yoshioka Yasukiyo;Sasada Tatsuya;Miyoshi Noriyuki
螺旋藻作为保健食品广为消费者所知，主要是一种干燥产品。由于原料螺旋藻作为蛋白质来源的数据是不够的，干燥和原料螺旋藻饮食的营养价值在Wistar大鼠进行了测定。消化率系数显著低于干饲料（84.1 ± 0.5%）和原始（85.7 ± 0.4）%，高于酪蛋白组（96.6 ± 0.2%），干饲料（86.3 ± 1.3%）和生饲料（77.9 ± 2.6%）的生物学效价显著高于酪蛋白饲料（71.9 ± 2.5%）。生螺旋藻蛋白质消化率校正氨基酸评分（86.6 ± 0.5%）显著高于干螺旋藻（85.1 ± 0.5%）。此外，螺旋藻饮食喂养大鼠门静脉血的氨基酸谱显示，Ala，Gly，瓦尔和Leu/Ile在体循环后显著降低。这些结果表明，干燥和生螺旋藻饮食可能不仅是有效的蛋白质来源，而且作为补充剂，以支持蛋白质/氨基酸的生物利用度。
Spirulina widely known to consumers as a health food is mainly a dried product. Since data for raw spirulina as a protein source are insufficient, the nutritional values of dry and raw spirulina diets in Wistar rats were determined. Digestibility coefficients were significantly lower in the dry (84.1 ± 0.5%) and raw (85.7 ± 0.4%) spirulina diets than that in the casein diet (96.6 ± 0.2%), although biological values of dry (86.3 ± 1.3%) and raw (77.9 ± 2.6%) spirulina diets were significantly higher than that of the casein diet (71.9 ± 2.5%). The protein digestibility-corrected amino acid score of raw spirulina (86.6 ± 0.5%) was significantly higher than that of dry spirulina (85.1 ± 0.5%). Additionally, amino acid profiling of portal/venous blood in spirulina diet-fed rats revealed that Ala, Gly, Val, and Leu/Ile were markedly decreased after systemic circulation. These results suggest that dry and raw spirulina diets may be effective not only as a protein source but also as a supplement to support protein/amino acid bioavailability.