The Frontal Assessment Battery (FAB): Normative values in an Italian population sample

The Frontal Assessment Battery (FAB): Normative values in an Italian population sample
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DOI:
10.1007/s10072-005-0443-4
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发表时间:
2005-06-01
影响因子:
3.3
通讯作者:
Nichelli, P
Nichelli, P
中科院分区:
医学4区
文献类型:
--
作者:
Appollonio, I;Leone, M;Nichelli, P

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额叶评估组合(FAB)是一种简短的认知和行为六项子测试组合,用于全球执行功能障碍的床边筛查;虽然最近设计,但由于其易于管理和声称的敏感性,它已经被广泛使用。本研究的目的是从不同年龄(平均:57.4 ± 17.9岁;范围:20-94岁)和教育水平(平均:10.4 ± 4.3岁)的364名对照受试者(215名女性和149名男性)的样本中得出意大利标准值。范围:1-17岁);同时进行简易精神状态检查(MMSE)。多元线性回归分析显示,年龄和教育的显着影响,而性别是不显着的,因此,从推导出的线性方程,建立了一个校正网格的FAB原始分数。基于非参数技术,随后确定推断截止评分并计算等效评分(ES)。测验-再测验信度和评定者间信度均令人满意。有趣的是,MMSE与FAB原始评分显著相关,而调整后的评分则不相关。目前的数据可以提高FAB用于临床和研究目的的准确性。
The Frontal Assessment Battery (FAB) is a short cognitive and behavioural six-subtest battery for the bedside screening of a global executive dysfunction; although recently devised, it is already extensively used thanks to its ease of administration and claimed sensitivity. The aim of the present study was to derive Italian normative values from a sample of 364 control subjects (215 women and 149 men) of different ages (mean: 57.4 +/- 17.9 years; range: 20-94 years) and educational level (mean: 10.4 +/- 4.3 years.; range: 1-17 years); the Mini Mental State Examination (MMSE) was concurrently administered. Multiple linear regression analysis revealed significant effects for age and education whereas gender was not significant; thus, from the derived linear equation, a correction grid for FAB raw scores was built. Based on nonparametric techniques, inferential cut-off scores were subsequently determined and equivalent scores (ES) computed. Test-restest and inter-rater reliabilities were both satisfactory. Interestingly, MMSE was significantly correlated with FAB raw scores, whereas adjusted scores were not. The present data may improve the accuracy in the use of the FAB both for clinical and research purposes.