Convenience is the key to hepatitis A and B vaccination uptake among young adult injection drug users
Convenience is the key to hepatitis A and B vaccination uptake among young adult injection drug users
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DOI：
10.1016/j.drugalcdep.2006.09.022
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发表时间：
2007-11-01
影响因子：
4.2
通讯作者：
Weinbaum, Cindy
中科院分区：
文献类型：
--
作者：
Campbell, Jennifer V.;Garfein, Richard S.;Weinbaum, Cindy
背景资料：尽管CDC建议注射吸毒者（IDUs）接种甲型肝炎病毒（HAV）和B肝炎病毒（HBV）感染疫苗，但覆盖率仍然很低。方便注射吸毒者的疫苗接种方案尚未得到广泛实施或评价。我们评估是否方便和金钱的激励措施影响摄取免费疫苗的18-30岁的注射吸毒者在五个美国countries.Methods：注射吸毒者招募从社区设置完成的风险行为自我访谈和测试抗体甲型肝炎病毒（抗-HAV）和肝炎B核心抗原（抗-HBc）。疫苗提供假定在预测试（除了在芝加哥）;现场的可用性和疫苗接种的激励不同的网站，创建一个准实验design.Results：3181参与者，抗-HAV和抗-HBc血清阳性率分别为19%和23%。虽然83%的参与者愿意接种疫苗，但只有36%的人接种了>= 1剂，这因地点而异：巴尔的摩（83%），西雅图（33%），洛杉矶（18%），纽约（17%）和芝加哥（2%）。在现场立即提供疫苗时，参与率最高，在收到结果后才提供疫苗时，参与率最低。金钱奖励可能增加了参与现场疫苗接种是不可用的。结论：注射吸毒者愿意接种疫苗，但立即，现场可用性是至关重要的摄取。在设计提高注射吸毒者疫苗接种率的战略时，便利应是一个关键考虑因素。(C)2007年由Elsevier爱尔兰有限公司出版。
Background: Despite CDC recommendations to vaccinate injection drug users (IDUs) against hepatitis A virus (HAV) and hepatitis B virus (HBV) infections, coverage remains low. Vaccination programs convenient to IDUs have not been widely implemented or evaluated. We assessed whether convenience and monetary incentives influenced uptake of free vaccine by 18-30-year-old IDUs in five U.S. cities.Methods: IDUs recruited from community settings completed risk behavior self-interviews and testing for antibodies to HAV (anti-HAV) and hepatitis B core antigen (anti-HBc). Vaccine was offered presumptively at pre-test (except in Chicago); on-site availability and incentives for vaccination differed by site, creating a quasi -experimental design.Results: Of 3181 participants, anti-HAV and anti-HBc seroprevalence was 19% and 23%, respectively. Although 83% of participants were willing to be vaccinated, only 36% received >= I dose, which varied by site: Baltimore (83%), Seattle (33%), Los Angeles (18%), New York (17%), and Chicago (2%). Participation was highest when vaccine was available immediately on-site and lowest when offered only after receiving results. Monetary incentives may have increased participation when on-site vaccination was not available.Conclusion: IDUs were willing to be vaccinated but immediate, on-site availability was critical for uptake. Convenience should be a key consideration in designing strategies to increase vaccine coverage among IDUs. (C) 2007 Published by Elsevier Ireland Ltd.