Pseudo-Gaucher cells in mycobacterial infection: a report of two cases
Pseudo-Gaucher cells in mycobacterial infection: a report of two cases
复制标题
DOI：
10.1136/jcp.2004.018176
复制
发表时间：
2005-10-01
影响因子：
3.4
通讯作者：
Sun, CF
中科院分区：
文献类型：
--
作者：
Dunn, P;Kuo, MC;Sun, CF
本文报告两例假戈谢氏细胞分枝杆菌感染病例。两例患者均无遗传性戈谢病的临床证据。第一个病例是艾滋病和鸟分枝杆菌细胞内累及肺、脾和骨髓的患者。骨髓抽吸可见大量组织细胞，呈针状包涵体。抗酸染色显示这些组织细胞含有抗酸杆菌。骨髓活检显示肉芽肿病变伴泡沫组织细胞聚集。第二例为酒精患者，卡那萨西分枝杆菌感染累及肺和淋巴结。淋巴结抽吸显示细胞质中有抗酸杆菌浸润的相同细胞。
This report describes two cases of mycobacterial infection with pseudo-Gaucher cells. Both patients had no clinical evidence of inherited Gaucher disease. The first case was a patient with AIDS and Mycobacterium avium intracellulare involving the lung, spleen, and bone marrow. The bone marrow aspirates showed many histiocytes with needle-like inclusions. Acid fast staining showed that these histiocytes contained acid fast bacilli. Bone marrow biopsies revealed granulomatous lesions with aggregates of foamy histiocytes. The second case was an alcoholic patient with Mycobacterium kanasassi infection involving the lung and lymph nodes. The lymph node aspirates showed infiltration of the same cells with acid fast bacilli in the cytoplasm.