Neuropsychological executive functions and DSM-IV ADHD subtypes

Neuropsychological executive functions and DSM-IV ADHD subtypes
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DOI:
10.1097/00004583-200201000-00012
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发表时间:
2002-01-01
影响因子:
13.3
通讯作者:
Rappley, MD
Rappley, MD
中科院分区:
医学1区
文献类型:
--
作者:
Nigg, JT;Blaskey, LG;Rappley, MD

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目的:评估和比较DSM-IV中注意缺陷/多动障碍合并型(ADHD-C)和注意力不集中型(ADHD-I)亚型的一组重点神经心理执行功能。方法:对105名年龄在7-12岁的adhd - iv - c型(n = 46)、ADHD-I型(n = 18)和社区控制型(n = 41)的男孩和女孩进行停止任务、伦敦塔任务、Stroop任务、造径测试和输出速度测量。结果:两种亚型在输出速度上均存在缺陷。在停止任务中观察到一组性别相互作用:ADHD-C的男孩比ADHD-I的男孩受损,而两种亚型的女孩没有差异。ADHD-C型在计划方面有缺陷。两个ADHD组在干扰控制方面都没有缺陷,尽管他们在Stroop任务上比对照组慢。结论:ADHD-I与ADHD-C在输出速度领域具有相同的神经心理缺陷;在大多数域上,亚型没有差异。这些ADHD亚型之间的神经心理学差异可能很少,这取决于评估执行功能的哪个领域,这些差异因性别而异。在男孩的病例中,这两种亚型可以通过运动抑制缺陷对ADHD-C的特异性来区分。
Objective: To evaluate and compare a focused set of component neuropsychological executive functions in the DSM-IV attention-deficit/hyperactivity disorder combined (ADHD-C) and inattentive (ADHD-I) subtypes. Method: The Stop task, Tower of London, Stroop task, Trailmaking Test, and output speed measures were completed by 105 boys and girls aged 7-12 classified as either DSM-IV ADHD-C (n = 46), ADHD-I (n = 18), or community control (n = 41). Results: Both subtypes had deficits on output speed. A group x gender interaction was observed on the Stop task: boys with ADHD-C were impaired versus boys with ADHD-I, whereas girls in the two subtypes did not differ. The ADHD-C type had a deficit in planning. Neither ADHD group had a deficit in interference control per se, although they were slower than controls on the Stroop tasks. Conclusions: ADHD-I shares neuropsychological deficits with ADHD-C in the domain of output speed; on most domains the subtypes did not differ. Neuropsychological distinctions between these ADHD subtypes may be few, depending on which domain of executive functioning is assessed, and these distinctions differ by gender. In the case of boys, the two subtypes may be distinguished by the specificity, of motor inhibition deficits to ADHD-C.