Delayed Administration of Antibiotics Beyond the First Hour of Recognition Is Associated with Increased Mortality Rates in Children with Sepsis/Severe Sepsis and Septic Shock
Delayed Administration of Antibiotics Beyond the First Hour of Recognition Is Associated with Increased Mortality Rates in Children with Sepsis/Severe Sepsis and Septic Shock
复制标题
DOI：
10.1016/j.jpeds.2020.12.035
复制
发表时间：
2021-05-21
影响因子：
5.1
通讯作者：
Kabra, Sushil K.
中科院分区：
文献类型：
--
作者：
Sankar, Jhuma;Garg, Mohil;Kabra, Sushil K.
目的比较脓毒症、严重脓毒症或脓毒性休克患儿在确诊后1小时内接受抗生素治疗（早期抗生素组）与1小时后接受抗生素治疗（延迟抗生素组）的死亡率和其他临床结局风险。
Objective To compare the risk of mortality and other clinical outcomes in children with sepsis, severe sepsis, or septic shock who received antibiotics within the first hour of recognition (early antibiotics group) with those who received antibiotics after the first hour (delayed antibiotics group).Study design In this prospective cohort study, we enrolled children