Mechanical model of the breast for the prediction of deformation during imaging

Mechanical model of the breast for the prediction of deformation during imaging
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DOI:
10.1016/j.medengphy.2012.06.012
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发表时间:
2013-04-01
影响因子:
2.2
通讯作者:
Federico, S.
Federico, S.
中科院分区:
工程技术3区
文献类型:
--
作者:
Kuhlmann, M.;Fear, E. C.;Federico, S.

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为了预测不同成像设备中乳房形状的变化,开发了耦合欧拉-拉格朗日(CEL)力学模型。CEL方法允许更充分地表示乳房的软组织和不可压缩组织所经历的非常大的变形。组织的机械响应基于先进的数学公式和文献中的实验数据。从磁共振(MR)图像生成的逼真的几何形状被用作研究案例。此外,特定的边界条件被施加到模型中,以预测乳房的形状和内部组织在原型微波乳房成像系统中的位置,其中使用浸没介质。通过比较数值结果与微波乳腺成像系统中同一受试者的激光扫描,评估模型的准确性。(C)2012年IPEM。由爱思唯尔有限公司出版。保留所有权利。
To predict changes in the shape of the breast in different imaging devices, a Coupled Eulerian-Lagrangian (CEL) mechanical model is developed. The CEL method allows for a more adequate representation of the very large deformations experienced by the soft and incompressible tissues of the breast. The mechanical response of the tissues is based on advanced mathematical formulations and experimental data from the literature. Realistic geometries generated from Magnetic Resonance (MR) images are used as study cases. Furthermore, specific boundary conditions are applied to the model to predict the shape of the breast and the location of the internal tissues in a prototype microwave breast imaging system, where an immersion medium is used. The accuracy of the model was assessed by comparing the numerical results with a laser scan of the same subject in the microwave breast imaging system. (C) 2012 IPEM. Published by Elsevier Ltd. All rights reserved.