MARITAL QUALITY, MARITAL DISRUPTION, AND IMMUNE FUNCTION

MARITAL QUALITY, MARITAL DISRUPTION, AND IMMUNE FUNCTION
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DOI:
10.1097/00006842-198701000-00002
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发表时间:
1987-01-01
影响因子:
3.3
通讯作者:
GLASER, R
GLASER, R
中科院分区:
医学3区
文献类型:
--
作者:
KIECOLTGLASER, JK;FISHER, LD;GLASER, R

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婚姻破裂与各种心理和身体疾病的显著增加有关。为了研究心理和生理介质,自我报告的数据和血液样本,从38名已婚妇女和38名分居/离婚妇女。在已婚受试者中,较差的婚姻质量与更大的抑郁症和免疫功能的三个定性指标的反应较差有关。与社会人口学匹配的已婚妇女相比,分居1年或更短时间的妇女的免疫功能在定性和定量方面明显较差。在分居/离婚的队列中,较短的分居时间和对(前夫)丈夫的依恋与免疫功能较差和抑郁程度较高有关。这些数据与流行病学证据相一致,将婚姻破裂与发病率和死亡率增加联系起来。
Marital disruption is associated with significant increases in a variety of psychologic and physical disorders. In order to examine psychologic and physiologic mediators, self-report data and blood samples were obtained from 38 married women and 38 separated/divorced women. Among married subjects, poorer marital quality was associated with greater depression and a poorer response on three qualitative measures of immune function. Women who had been separated 1 year or less and significantly poorer qualitative and quantitative immune function than their sociodemographically matched married counterparts. Among the separated/divorced cohort, shorter separation periods and greater attachment to the (ex)husband wre associated with poorer immune function and greater depression. These data are consistent with epidemiologic evidence linking marital disruption with increased morbidity and mortality.