Economic evaluation of implementation science outcomes in low- and middle-income countries: a scoping review.
Economic evaluation of implementation science outcomes in low- and middle-income countries: a scoping review.
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DOI：
10.1186/s13012-022-01248-x
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发表时间：
2022-11-16
影响因子：
7.2
通讯作者：
Dowdy, David W.
中科院分区：
文献类型：
--
作者：
Malhotra, Akash;Thompson, Ryan R.;Kagoya, Faith;Masiye, Felix;Mbewe, Peter;Mosepele, Mosepele;Phiri, Jane;Sambo, Jairos;Barker, Abigail;Cameron, Drew B.;Davila-Roman, Victor G.;Effah, William;Hutchinson, Brian;Laxy, Michael;Newsome, Brad;Watkins, David;Sohn, Hojoon;Dowdy, David W.
关键词：
从历史上看，成本效益分析的重点一直放在干预措施最初设计和启动后的操作和交付成本上。与设计和实施干预措施有关的费用常常被忽略。忽视这些成本会导致低估干预措施的真实价格，并使经济分析偏向于支持新的干预措施。在低收入和中等收入国家尤其如此，这些国家的实施可能需要大量的前期投资。本综述旨在探讨将实施科学纳入中低收入国家卫生干预措施经济评估的科学文献的主题、深度和可得性。我们在Web of Science和PubMed检索了2010年1月1日至2021年12月31日之间发表的论文，其中包括实施科学和经济评估的组成部分。来自中低收入国家的研究被列为优先审查对象，但来自高收入国家的论文如果其方法/发现与中低收入国家的环境相关，则被纳入审查范围。筛选了六千九百八十六项研究，其中55项纳入全文综述，23项纳入和数据提取。大多数论文都是理论性的，尽管有些论文专注于单一疾病或疾病子集，包括：精神健康（n = 5）、艾滋病毒（n = 3）、结核病（n = 3）和糖尿病（n = 2）。手稿包括方法论论文、实证研究和其他（例如，叙述）评论的混合。纳入的文献的作者倾向于高收入国家，23篇论文中有22篇的第一作者和资深作者来自高收入国家。在包括的9项实证研究中，没有衡量一致的实施成本结果，只有4项可以映射到现有的成本或实施框架。在如何定义实施成本和收集成本的方法方面，各研究之间也存在很大的异质性。很少但不断增长的文献探讨了实施科学和经济评估的交集。关键需求包括加强对中低收入国家的研究，就实施成本的定义达成更大的共识，收集此类成本的标准化方法，以及确定最相关的成果。解决这些差距将导致在实施科学和经济评估之间建立更紧密的联系，并将对干预成本进行更可靠和准确的估计。本文的协议发表在开放科学框架上。它可以在：https://osf.io/ms5fa/ (DOI: 10.17605/OSF.IO/32EPJ)获得。在线版本包含补充资料，网址为10.1186/s13012-022-01248-x。
Historically, the focus of cost-effectiveness analyses has been on the costs to operate and deliver interventions after their initial design and launch. The costs related to design and implementation of interventions have often been omitted. Ignoring these costs leads to an underestimation of the true price of interventions and biases economic analyses toward favoring new interventions. This is especially true in low- and middle-income countries (LMICs), where implementation may require substantial up-front investment. This scoping review was conducted to explore the topics, depth, and availability of scientific literature on integrating implementation science into economic evaluations of health interventions in LMICs. We searched Web of Science and PubMed for papers published between January 1, 2010, and December 31, 2021, that included components of both implementation science and economic evaluation. Studies from LMICs were prioritized for review, but papers from high-income countries were included if their methodology/findings were relevant to LMIC settings. Six thousand nine hundred eighty-six studies were screened, of which 55 were included in full-text review and 23 selected for inclusion and data extraction. Most papers were theoretical, though some focused on a single disease or disease subset, including: mental health (n = 5), HIV (n = 3), tuberculosis (n = 3), and diabetes (n = 2). Manuscripts included a mix of methodology papers, empirical studies, and other (e.g., narrative) reviews. Authorship of the included literature was skewed toward high-income settings, with 22 of the 23 papers featuring first and senior authors from high-income countries. Of nine empirical studies included, no consistent implementation cost outcomes were measured, and only four could be mapped to an existing costing or implementation framework. There was also substantial heterogeneity across studies in how implementation costs were defined, and the methods used to collect them. A sparse but growing literature explores the intersection of implementation science and economic evaluation. Key needs include more research in LMICs, greater consensus on the definition of implementation costs, standardized methods to collect such costs, and identifying outcomes of greatest relevance. Addressing these gaps will result in stronger links between implementation science and economic evaluation and will create more robust and accurate estimates of intervention costs. The protocol for this manuscript was published on the Open Science Framework. It is available at: https://osf.io/ms5fa/ (DOI: 10.17605/OSF.IO/32EPJ). The online version contains supplementary material available at 10.1186/s13012-022-01248-x.
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影响因子：
12.7
作者：
Glasgow, RE;Vogt, TM;Boles, SM
通讯作者：
Boles, SM
DOI：
10.1186/1748-5908-4-50
发表时间：
2009-08-07
期刊：
Implementation science : IS
影响因子：
--
作者：
Damschroder LJ;Aron DC;Keith RE;Kirsh SR;Alexander JA;Lowery JC
通讯作者：
Lowery JC
DOI：
10.1186/s13012-015-0242-0
发表时间：
2015-04-21
期刊：
Implementation science : IS
影响因子：
--
作者：
Nilsen P
通讯作者：
Nilsen P
影响因子：
4.6
作者：
Krebs E;Nosyk B
通讯作者：
Nosyk B
影响因子：
--
作者：
McDonald, Kathryn M;Schultz, Ellen M;Chang, Christine
通讯作者：
Chang, Christine