Development of an endometriosis quality-of-life instrument: The endometriosis health profile-30
Development of an endometriosis quality-of-life instrument: The endometriosis health profile-30
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DOI：
10.1016/s0029-7844(01)01433-8
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发表时间：
2001-08-01
影响因子：
7.2
通讯作者：
Jenkinson, C
中科院分区：
文献类型：
--
作者：
Jones, G;Kennedy, S;Jenkinson, C
目的：描述一种新的疾病特异性问卷，建立测量属性，解决健康相关的生活质量的尺寸被认为是重要的妇女子宫内膜异位症。方法：子宫内膜异位症健康档案-30分三个阶段开发。第一阶段包括与25名妇女进行开放式探索性访谈，以生成问卷上的项目。第二阶段是一个87项问卷调查管理的邮政调查，以确定最显着的健康相关的生活质量的方面。在第三阶段，信度和效度进行了评估。结果：最终的工具包括一个核心问卷，30个项目和5个量表：疼痛，控制和无力感，情绪幸福感，社会支持，自我形象。还开发了由23个问题组成的六个模块部分，并测量了性交、工作、与儿童的关系、对医疗专业的感受、治疗和不孕症等领域。所有量表都达到了较高的内部信度，Cronbach的α系数范围为0.83至0.93（核心问卷）和0.79至0.96（模块）。评价重测信度的组内相关系数较高（范围0.88-0.98，P <0.001）。内容效度被证明为问卷是从病人的访谈，而不是现有的文献和临床量表。通过将子宫内膜异位症健康状况-30量表与相关简表-36量表相关联来评估结构效度。所有比较的高相关性被发现（-0.41至-0.73）。结论：子宫内膜异位症健康状况-30是一个可靠的，有效的，病人产生的工具来衡量健康相关的生活质量的妇女子宫内膜异位症。它在各种医疗机构的应用将提供新的和有价值的信息，子宫内膜异位症的影响健康相关的生活质量从患者的角度来看。(C)2001年由美国妇产科医师学会。
OBJECTIVE: To describe a new disease-specific questionnaire with established measurement properties that addresses the dimensions of health-related quality of life considered important to women with endometriosis.METHODS: The Endometriosis Health Profile-30 was developed in three stages. Stage 1 included open-ended exploratory interviews with 25 women to generate the items on the questionnaire. Stage 2 was an 87-item questionnaire administered in a postal survey to identify the most salient dimensions of health-related quality of life. In stage 3, the reliability and validity of the questionnaire were evaluated.RESULTS: The final instrument contained a core questionnaire with 30 items and five scales: pain, control and powerlessness, emotional well-being, social support, and self-image. Six modular parts consisting of 23 questions were also developed and measured the areas of sexual intercourse, work, relationship with children, feelings about the medical profession, treatment, and infertility. All the scales achieved high internal reliability, with Cronbach's alpha coefficient ranging from 0.83 to 0.93 (core questionnaire) and 0.79 to 0.96 (modules). The intraclass correlation coefficients to evaluate the test-retest reliability were high (range 0.88-0.98, P < .001). Content validity was demonstrated as the questionnaire was developed from interviews of patients rather than existing literature and clinical scales. Construct validity was assessed by correlating the Endometriosis Health Profile-30 scales with the relevant Short Form-36 scales. High correlations for all comparisons were found (-0.41 to -0.73).CONCLUSION: The Endometriosis Health Profile-30 is a reliable, valid, patient-generated instrument to measure the health-related quality of life of women with endometriosis. Its application in various health care settings will provide new and valuable information on the effect of endometriosis on health-related quality of life from the patients' perspective. (C) 2001 by the American College of Obstetricians and Gynecologists.