Generalized Anxiety Disorder Is Associated with Metabolic Syndrome in the Vietnam Experience Study
Generalized Anxiety Disorder Is Associated with Metabolic Syndrome in the Vietnam Experience Study
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DOI：
10.1016/j.biopsych.2009.02.020
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发表时间：
2009-07-01
影响因子：
10.6
通讯作者：
Batty, G. David
中科院分区：
文献类型：
--
作者：
Carroll, Douglas;Phillips, Anna C.;Batty, G. David
背景资料：很少有研究探讨主要精神健康障碍和代谢综合征（MetS）之间的关系，尽管两者都与心血管疾病有关。本研究探讨了横截面协会的严重抑郁症（MDD）和广泛性焦虑症（GAD）与代谢综合征在一个大型研究的男性美国veterinary.Methods：分析是横截面。参与者（n = 4256）来自越南经验研究。从兵役档案，电话采访，体检，职业，社会人口和健康数据收集。MDD和GAD的一年患病率采用DSM-III标准确定。代谢综合征的数据包括：体重指数、空腹血糖或糖尿病诊断、血压、高密度脂蛋白胆固醇和甘油三酯水平。在根据年龄调整的模型中，（p = .01），此外还有服役地点、种族、婚姻状况、吸烟、饮酒、入伍时的智商、中年家庭收入，GAD与MetS呈正相关（P = 0.02）。重度抑郁症与MetS.Conclusions：抑郁症一直是心理健康和身体健康结果研究的重点条件。目前的数据表明，未来的研究可能应该同样重视广泛性焦虑症。
Background: Few studies have explored the relationship between major mental health disorders and metabolic syndrome (MetS), although both have been linked to cardiovascular disease. The present study examined the cross-sectional associations of major depressive disorder (MDD) and generalized anxiety disorder (GAD) with MetS in a large study of male US veterans.Methods: The analyses were cross-sectional. Participants (n = 4256) were drawn from the Vietnam Experience Study. From military service files, telephone interviews, and a medical examination, occupational, socio-demographic, and health data were collected. One-year prevalence of MDD and GAD was determined with DSM-III criteria. Metabolic syndrome was ascertained from data on: body mass index, fasting blood glucose or a diagnosis of diabetes, blood pressure, high-density lipoprotein cholesterol, and triglyceride levels.Results: In models that adjusted for age (p = .01) and additionally for place of service, ethnicity, marital status, smoking, alcohol consumption, IQ at enlistment, household income in midlife, and education grade achieved (p = .02), GAD was positively associated with MetS. Major depressive disorder was not related to MetS.Conclusions: Depression has very much been the focal condition for studies on mental health and physical health outcomes. The current data suggest that future research should perhaps pay equal attention to GAD.