Studies on the green liver in cultured red sea bream fed low level and non-fish meal diets: Relationship between hepatic taurine and biliverdin levels
Studies on the green liver in cultured red sea bream fed low level and non-fish meal diets: Relationship between hepatic taurine and biliverdin levels
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DOI：
10.1046/j.1444-2906.2001.00199.x
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发表时间：
2001-02-01
影响因子：
1.9
通讯作者：
Murata, H
中科院分区：
文献类型：
--
作者：
Goto, T;Takagi, S;Murata, H
本研究的目的是调查饲喂替代蛋白饲料的红鲷鱼出现绿肝的原因。红鲷在 28 周内接受以下任一饮食：(1) 对照饮食（50% 鱼粉），(2) 低水平鱼粉饮食（15% 鱼粉），以及（3）非鱼粉饮食（0% 鱼粉）。所有测试组均观察到绿色肝脏，但实验饮食组的发生率要高得多。替代蛋白饮食的喂养降低了血浆甘油三酯和胆固醇水平。然而，各处理之间血浆肝酶活性和血浆胆汁盐浓度没有显着差异。饲喂替代蛋白饲料的鱼的肝脏牛磺酸水平较低，肝脏中出现胆绿素。此外，在喂食替代蛋白饲料的鱼中，双牛胆红素占总胆汁色素的比例显着降低。这些数据表明，饲喂替代蛋白饲料不会引起任何胆汁淤积性肝胆梗阻，并且肝脏牛磺酸水平低是导致饲喂替代蛋白饲料的红鲷鱼出现绿肝的可能因素之一。
The aim of this study was to investigate the cause of green liver in red sea bream fed substitute protein diets. Red sea bream Pagrus major was given either of the following diets for 28 weeks: (1) control diet (50% fish meal), (2) low level fish meal diet (15% fish meal), and (3) non-fish meal diet (0% fish meal). The green liver was observed in all groups tested, but the incidence was much higher in the experimental diet groups. The feeding of substitute protein diets reduced plasma triglyceride and cholesterol levels. However, there was no significant difference in plasma hepatic enzyme activities and plasma bile salts concentration among the treatments. Fish fed the substitute protein diets showed low hepatic taurine levels with an appearance of a biliverdin in the liver. Moreover, the proportion of ditaurobilirubin to total biliary bile pigments was significantly lower in fish fed the substitute protein diets. These data indicate that feeding of substitute protein diets did not induce any cholestatic hepatobiliary obstructions and that the low hepatic taurine level was one of the probable factors responsible for the occurrence of green liver in red sea bream fed substitute protein diets.