Natural product-derived drugs for the treatment of inflammatory bowel diseases.
Natural product-derived drugs for the treatment of inflammatory bowel diseases.
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天然产物衍生的药物用于治疗炎症性肠病。
DOI：
10.5217/ir.2014.12.2.103
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发表时间：
2014-04
影响因子：
4.9
通讯作者：
Joo YE
中科院分区：
文献类型：
--
作者：
Joo YE
天然产品被用作药物已有数千年的历史，对天然产品的治疗潜力的研究已有一个多世纪的历史。自19世纪80年代中期以来，大约60%的药物来自天然产品。最近，使用天然产品的重要性增加了，人们对发现有效的新药的兴趣也增加了。天然药物是治疗炎症性肠病的理想药物，如溃疡性结肠炎和克罗恩病。本文综述了从天然产物中提取的治疗炎症性肠病药物的发现和发展。
Natural products have been used as drugs for millennia, and the therapeutic potential of natural products has been studied for more than a century. Since the mid-1880s, approximately 60% of drugs have originated from natural products. Recently, the importance of using natural products has increased, as has interest in discovering efficient new drugs. Natural drugs are desirable for the treatment of inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease. This review discusses the discovery and development of drugs derived from natural products for the treatment of inflammatory bowel diseases.