Bilateral vitreous hemorrhage in a child due to isolated platelet factor 3 availability defect

Bilateral vitreous hemorrhage in a child due to isolated platelet factor 3 availability defect
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DOI:
10.1016/j.jaapos.2007.09.013
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发表时间:
2008-04-01
期刊:
影响因子:
1.6
通讯作者:
Garg, Satpal
Garg, Satpal
中科院分区:
医学4区
文献类型:
--
作者:
Naithani, Prashant;Mehrotra, Abbas;Garg, Satpal

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玻璃体出血是一种罕见的原因,儿童视力下降。我们报告一个三岁的小孩,因为单一的血小板因子3(PF-3)缺乏而导致双侧玻璃体出血。预防性输注富血小板血浆,然后在双眼进行睫状体平坦部玻璃体切除术,手术和视力结果良好。这份报告强调了详尽的血液学和血小板功能研究的重要性,在儿童提出了双边玻璃体出血和其管理的影响,目前和未来的出血事件。
Vitreous hemorrhage is an uncommon cause of decreased vision in children. We report a 3-year-old child with bilateral vitreous hemorrhage secondary to an isolated platelet factor 3 (PF-3) availability defect. Prophylactic infusion of platelet-rich plasma followed by pars plana vitrectomy in both eyes resulted in an excellent surgical and visual outcome. This report emphasizes the importance of exhaustive hematological and platelet function studies in a child presenting with bilateral vitreous hemorrhage and its implications on the management of present and future bleeding episodes.