Automated unwrapping of MR phase images applied to BOLD MR-Venography at 3 Tesla
Automated unwrapping of MR phase images applied to BOLD MR-Venography at 3 Tesla
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DOI：
10.1002/jmri.10346
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发表时间：
2003-08-01
影响因子：
4.4
通讯作者：
Moser, E
中科院分区：
文献类型：
--
作者：
Rauscher, A;Barth, M;Moser, E
目的：消除BOLD法MR静脉成像中与相位缠绕有关的伪影，提高其诊断价值。材料和方法：在3 T系统（Medspec 30/80 Avance.布鲁克医疗Ettlingen，德国）与三维。使用正交发射/接收鸟笼头部线圈的一阶速度补偿梯度回波序列。评价了9名健康受试者和19名患者的数据（年龄范围：27至76岁）。为了实现改进的MR-静脉图，一个完全自动化的区域增长相位展开算法和随后的高通滤波应用于相位图像之前的最小强度projects.Results的计算：显着改善可视化静脉结构的区域大的背景磁化率引起的领域不均匀性是证明在健康受试者和脑肿瘤患者。结论：与之前的后处理算法相比，BOLD MR静脉造影得到了改进。现在可以在非均匀区域获得高分辨率图像，这增加了BOLD MR静脉造影的临床潜力。
Purpose: To improve the diagnostic value of BOLD MR-Venography by removing artifacts related to phase wrapping. particularly in regions of large background susceptibilities at high magnetic field strengths.Materials and Methods: High resolution, T-2*-weighted, single echo images were acquired on a 3 T system (Medspec 30/80 Avance. Bruker Medical. Ettlingen, Germany) with a three-dimensional. first order velocity compensated gradient echo sequence using a quadrature transmit/receive birdcage head coil. Data of nine healthy subjects and 19 patients were evaluated (age range: 27 to 76 years). To achieve improved MR-venograms, a fully automated region-growing phase unwrapping algorithm and subsequent high pass filtering were applied to phase images prior to the computation of minimum intensity projections.Results: Considerably improved visualization of venous structures in regions of large background susceptibility-induced field inhomogeneities is demonstrated in healthy subjects and patients with brain tumors.Conclusion: BOLD MR venograms are improved compared to previous post-processing algorithms. It is now feasible to obtain high-resolution images also in inhomogeneous regions, which increases the clinical potential of BOLD MR-Venography.