[H-3] THYMIDINE LABELING OF DERMAL ENDOTHELIAL CELLS IN SCLERODERMA

[H-3] THYMIDINE LABELING OF DERMAL ENDOTHELIAL CELLS IN SCLERODERMA
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DOI:
10.1111/1523-1747.ep12510308
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发表时间:
1977-01-01
影响因子:
6.5
通讯作者:
PERLISH, JS
PERLISH, JS
中科院分区:
医学1区
文献类型:
--
作者:
FLEISCHMAJER, R;PERLISH, JS

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本研究的目的是评估(3H]胸腺嘧啶核苷标记的皮肤毛细血管内皮细胞局限性硬皮病(LS)和系统性硬皮病(SS)。通过体外放射自显影研究了14例SS患者、5例LS患者和9例匹配对照的皮肤标本。与对照组相比,SS患者的血管内皮细胞标记显示统计学显著增加(P < 0.0005)。
The purpose of this study was to estimate (3H]thymidine labeling of endothelial cells of skin capillaries in localized scleroderma (LS) and systemic scleroderma (SS). Skin specimens from 14 patients with SS, 5 with LS, and 9 matched controls were studied by in vitro autoradiography. Capillaries from patients with SS showed a statistically significant increase in endothelial cell labeling when compared to vessels from controls (P < 0.0005).