The Value of Laparoscopic Simultaneous Colorectal and Hepatic Resection for Synchronous Colorectal Cancer Liver Metastasis: A Propensity Score Matching Study.
The Value of Laparoscopic Simultaneous Colorectal and Hepatic Resection for Synchronous Colorectal Cancer Liver Metastasis: A Propensity Score Matching Study.
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腹腔镜同时结直肠癌和肝切除术对同步结直肠癌肝转移的价值：倾向评分匹配研究
DOI：
10.3389/fonc.2022.916455
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发表时间：
2022
影响因子：
4.7
通讯作者：
Wang, Lu
中科院分区：
文献类型：
--
作者：
Zhou, Jiamin;Feng, Longhai;Li, Xinxiang;Wang, Miao;Zhao, Yiming;Zhang, Ning;Wang, Longrong;Zhang, Ti;Mao, Anrong;Xu, Ye;Wang, Lu
本研究的目的是探讨全腹腔镜下结直肠癌肝转移患者行结直肠癌肝切除术的价值。回顾性分析了2014年12月至2018年12月在复旦大学附属肿瘤医院行同期切除术的sCRLM患者。患者分为腹腔镜手术组、开放手术组和混合手术组。比较三组患者的术中信息、术后近期疗效和长期生存率。进行倾向评分匹配（PSM）以平衡基线。共招募了281名患者。PSM后，从腹腔镜和开放手术组中选择34例患者。还从腹腔镜和混合手术组中选择了47例患者。腹腔镜手术组与其他两组的临床病理基线匹配良好。腹腔镜手术与杂交手术的所有手术相关指标相似。然而，与开放手术相比，腹腔镜手术的手术时间显著更长（229.09 ± 10.94 min vs. 192.24 ± 9.49 min，p = 0.013），术中失血量更少[100.00（50.00-300.00）ml vs. 200.00（150.00-400.00）ml，p = 0.021]。对于术后发病率，腹腔镜手术组与混合或开放手术组之间无显著差异（23.40% vs. 31.91%和17.65% vs. 26.47%，p = 0.356和p = 0.380）。长期生存分析显示，腹腔镜手术和混合手术之间的1年、3年和5年总生存期、肝脏无复发生存期（RFS）和整体RFS没有显着差异（p = 0.334、p = 0.286和p = 0.558）或开放手术（p = 0.230、p = 0.348和p = 0.450）。腹腔镜下同时切除sCRLM在手术安全性和短期结局方面略有优势，并且不会影响长期生存。
The aim of this study is to investigate the value of total laparoscopic simultaneous colorectal and hepatic resection in patients with synchronous colorectal cancer liver metastases (sCRLMs). sCRLM patients who underwent simultaneous resection from December 2014 to December 2018 in Shanghai Cancer Center, Fudan University were recruited and analyzed retrospectively. The patients were divided into laparoscopic, open, and hybrid surgery groups. The intraoperative information, postoperative short-term outcome, and long-term survival were compared among the three groups. Propensity score matching (PSM) was performed to balance baselines. A total of 281 patients were recruited. After PSM, 34 patients were selected from both the laparoscopic and the open surgery group. Forty-seven patients were also selected from both the laparoscopic and the hybrid surgery group. The clinicopathologic baselines between the laparoscopic surgery group and the other two groups were well matched. All the operation-related indicators between laparoscopic surgery and hybrid surgery were similar. However, compared with open surgery, laparoscopic surgery showed significantly longer operation time (229.09 ± 10.94 min vs. 192.24 ± 9.49 min, p = 0.013) and less intraoperative blood loss [100.00 (50.00–300.00) ml vs. 200.00 (150.00–400.00) ml, p = 0.021]. For postoperative morbidity, there was no significant difference between the laparoscopic surgery group and the hybrid or the open surgery group (23.40% vs. 31.91% and 17.65% vs. 26.47%, p = 0.356 and p = 0.380). Long-term survival analysis showed that there were no significant differences in all 1-, 3-, and 5-year overall survival, liver recurrence-free survival (RFS), and whole RFS between laparoscopic surgery and hybrid surgery (p = 0.334, p = 0.286, and p = 0.558) or open surgery (p = 0.230, p = 0.348, and p = 0.450). Laparoscopic simultaneous resection for sCRLM shows slight advantages in surgical safety and short-term outcome, and does not compromise long-term survival.
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影响因子：
3.7
作者：
Giuliante F;Viganò L;De Rose AM;Mirza DF;Lapointe R;Kaiser G;Barroso E;Ferrero A;Isoniemi H;Lopez-Ben S;Popescu I;Ouellet JF;Hubert C;Regimbeau JM;Lin JK;Skipenko OG;Ardito F;Adam R
通讯作者：
Adam R
影响因子：
9.6
作者：
Abu Hilal, M.;Underwood, T.;Pearce, N.
通讯作者：
Pearce, N.
影响因子：
9
作者：
Margonis, Georgios Antonios;Amini, Neda;Weiss, Matthew J.
通讯作者：
Weiss, Matthew J.
影响因子：
3.5
作者：
Chen, Ying-Wei;Huang, Ming-Te;Chang, Tung-Cheng
通讯作者：
Chang, Tung-Cheng
DOI：
10.1007/s00464-019-07253-4
发表时间：
2019-11-15
影响因子：
3.1
作者：
Shin, Jung Kyong;Kim, Hee Cheol;Kim, Jong Man
通讯作者：
Kim, Jong Man