Evaluation of a new injury model to study medial collateral ligament healing: Primary repair versus nonoperative treatment
Evaluation of a new injury model to study medial collateral ligament healing: Primary repair versus nonoperative treatment
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研究内侧副韧带愈合的新损伤模型的评估：初次修复与非手术治疗
DOI：
10.1002/jor.1100090407
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发表时间：
1991
影响因子：
2.8
通讯作者：
P. Newton
中科院分区：
文献类型：
--
作者：
J. Weiss;S. Woo;K. Ohland;S. Horibe;P. Newton
家兔左后肢的内侧副韧带（MCL）被放置在其下方的棒断裂，导致韧带物质“拖把端”撕裂，同时损伤插入部位。使用这个模型，我们比较了初级韧带修复和非手术治疗的生物力学和组织学技术在时间零，10天，6和12周后。生物力学评价包括测量膝关节内翻-外翻（V-V）旋转、MCL上的原位载荷以及股骨-MCL-胫骨复合体（FMTC）的拉伸试验。所有实验膝关节的V-V旋转随时间推移而减少。在12周时，实验膝关节的V-V旋转仍然是对照膝关节的1.3倍。初次修复最初减少了V-V旋转，但在第6周和第12周，手术和非手术膝关节之间没有统计学差异。MCL上的原位负载遵循相同的趋势。MCL修复对任何拉伸性能均无显著影响。然而，术后愈合时间显著改善了两个实验组的FMTC结构特性。FMTCs和韧带止点的组织切片的失效模式表明，损伤后韧带止点到骨的恢复比韧带物质慢。FMTC的拉伸试验表明，即使在术后12周，愈合韧带材料的机械性能仍与对照组有显著差异。
The medial collateral ligament (MCL) of the rabbit left hindlimb was ruptured by a rod placed beneath it, resulting in a “mop‐end” tear of the ligament substance with simultaneous injury to the insertion sites. Using this model, we compared primary ligament repair and nonoperative treatment using biomechanical and histologic techniques at time zero, 10 days, and 6 and 12 weeks postoperatively. Biomechanical evaluation included measurement of varus‐valgus (V‐V) knee rotation, in situ load on the MCL, and tensile testing of the femur‐MCL‐tibia complex (FMTC). The V‐V rotation of all experimental knees decreased over time. At 12 weeks, V‐V rotation of experimental knees was still 1.3 times larger than that of controls. Primary repair initially decreased V‐V rotation, but at 6 and 12 weeks there was no statistical difference between operated and nonoperated knees. The in situ load on the MCL followed the same trends. There was no significant effect of MCL repair on any of the tensile properties. However, postoperative healing time significantly improved the FMTC structural properties in both experimental groups. Failure modes of the FMTCs and histologic sections of the ligament insertion sites indicated that after injury the ligament insertion to bone recovered more slowly than the ligament substance. Tensile testing of the FMTC showed that even at 12 weeks postoperatively the mechanical properties of the healed ligament material remained significantly different from those of the controls.
前交叉韧带横断对内侧副韧带愈合的影响。
DOI：
--
发表时间：
1990
期刊：
The Journal of bone and joint surgery. American volume
影响因子：
--
作者：
Woo,SL;Young,EP;Ohland,KJ;Marcin,JP;Horibe,S;Lin,HC
通讯作者：
Lin,HC
DOI：
10.1115/1.3108414
发表时间：
1988-05-01
影响因子：
1.7
作者：
LEE, TQ;WOO, SLY
通讯作者：
WOO, SLY
测量韧带张力随膝关节运动和骨骼成熟的变化。
DOI：
10.1115/1.2891125
发表时间：
1990
期刊：
Journal of biomechanical engineering
影响因子：
--
作者：
Woo,SL;Weiss,JA;Gomez,MA;Hawkins,DA
通讯作者：
Hawkins,DA