Improving patients' postoperative sleep: a randomized control study comparing subcutaneous with intravenous patient-controlled analgesia.
Improving patients' postoperative sleep: a randomized control study comparing subcutaneous with intravenous patient-controlled analgesia.
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改善患者术后睡眠：一项比较皮下镇痛与静脉自控镇痛的随机对照研究。
DOI：
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发表时间：
1999
影响因子：
3.8
通讯作者：
Richard F. Barrett
中科院分区：
文献类型：
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作者：
Lisa Dawson;K. Brockbank;Eloise C.J. Carr;Richard F. Barrett
100名接受大型整形或妇科手术的女性患者被随机分成两组，一组接受皮下病人自控镇痛(PCA)(静脉自控镇痛，剂量2.5 mg/1ml，锁定时间20分钟)，另一组接受静脉自控镇痛(PCA，剂量0.5 mg/1ml，锁定时间5分钟)。通过问卷调查和访谈法收集数据，评价干预前后疼痛评分、术后第一晚睡眠质量、术后恶心呕吐(PONV)及患者总体可接受性。皮下自控镇痛组疼痛程度更低(P<；0.001)，疼痛引起的睡眠障碍也更少(P<；0.01)。皮下自控镇痛似乎为患者提供了一种安全有效的止痛方法，并可能比静脉给药具有显著的优势。
One hundred female patients undergoing major reconstructive plastic or gynaecological surgery were randomized to either receive subcutaneous patient-controlled analgesia (PCA) (bolus dose 2.5 mg diamorphine in 1 ml with a 20-minute lockout) or intravenous PCA (bolus dose 0.5 mg diamorphine in 1 ml with a 5-minute lockout). Data were collected by questionnaire and interview to evaluate the intervention on pain scores, quality of sleep on the first postoperative night, postoperative nausea and vomiting (PONV) and overall patient acceptability. The subcutaneous PCA group experienced less 'worse pain' (P < 0.01) and less sleep disturbance due to pain (P < 0.001). Subcutaneous PCA would appear to offer patients a safe and effective means of analgesia and may offer significant advantages over the intravenous route of administration.