The RLK/Pelle family of kinases.
The RLK/Pelle family of kinases.
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DOI：
10.1111/j.1365-313x.2011.04518.x
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发表时间：
2011-04
期刊：
影响因子：
--
通讯作者：
Clark SE
中科院分区：
文献类型：
--
作者：
Gish LA;Clark SE
RLK/Pelle类蛋白激酶在拟南芥中由超过600个成员组成。该家族中的许多蛋白质是受体样激酶（RLK），而其他蛋白质失去了它们的细胞外结构域，并被发现为细胞质激酶。这个家族中的蛋白质是RLK，具有多种细胞外结构域，其在大量过程中驱动功能，从细胞壁相互作用到疾病抗性到发育控制。本文将简要介绍RLK/Pelle蛋白的主要亚类及其作用。此外，将详细讨论RLKs上的两个特定组，涉及拟南芥中的最新发现以及这些结论如何能够被翻译到农学上重要的物种。最后，激酶活性和信号转导的一些细节将被解决，沿着的神秘的RLK/Pelle成员缺乏激酶酶活性。
The RLK/Pelle class of proteins kinases is composed of over 600 members in Arabidopsis. Many of the proteins in this family are receptor-like kinases (RLK), while others have lost their extracellular domains and are found as cytoplasmic kinases. Proteins in this family that are RLKs have a variety of extracellular domains that drive function in a large number of processes, from cell wall interactions to disease resistance to developmental control. This review will briefly cover the major subclasses of RLK/Pelle proteins and their roles. In addition, two specific groups on RLKs will be discussed in detail, relating recent findings in Arabidopsis and how well these conclusions have been able to be translated to agronomically important species. Finally, some details on kinase activity and signal transduction will be addressed, along with the mystery of RLK/Pelle members lacking kinase enzymatic activity.