Induced negative arousal modulates the speed of visual working memory consolidation.
Induced negative arousal modulates the speed of visual working memory consolidation.
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DOI：
10.1037/emo0001059
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发表时间：
2022-03
期刊：
影响因子：
4.2
通讯作者：
Zhang, Weiwei
中科院分区：
文献类型：
--
作者：
Xie, Weizhen;Lu Sing, Jc Lynne;Martinez-Flores, Ana;Zhang, Weiwei
本研究探讨了诱发的负面唤醒如何影响脆弱的感官输入巩固为持久工作记忆（WM）表征。参与者执行了一个视觉WM变化检测任务，其编码时间由插入在不同水平的记忆和掩码刺激-启动-异步（SOA）上的随机模式掩码操纵。在WM任务之前，使用国际情感数字声音（IADS）的音频片段诱导消极或中性情绪。同时记录瞳孔测量以提供诱发性兴奋的客观测量。早期生活压力（即不良童年经历）和当前情绪状态（即抑郁情绪和焦虑感觉）的自我报告测量也被收集为协变量。我们发现，参与者在100毫秒的短记忆-面具SOA下，在不同情绪条件下，最初记住了相当数量的WM项目，但在诱发的负性唤醒下，在333毫秒的长记忆-面具SOA下，他们将更多的项目编码为WM。这些发现表明，诱发的负性唤醒加速了脑皮层的巩固。然而，诱导的负性唤醒似乎并没有显著影响参与者在单独的无面具条件下估计的WM存储容量。此外，情绪对记忆巩固速度的影响受关键情绪相关个体差异的调节。对负面IADS声音有更大瞳孔反应或有更多早期生活压力的参与者在诱导的负面唤醒下表现出更快的WM巩固。总的来说，我们的研究结果揭示了阶段性肾上腺素能反应在视觉WM内容快速巩固中的关键作用以及这种关联的潜在调节因素。
This study examines how induced negative arousal influences the consolidation of fragile sensory inputs into durable working memory (WM) representations. Participants performed a visual WM change detection task with different amounts of encoding time manipulated by random pattern masks inserted at different levels of memory-and-mask Stimulus-Onset-Asynchrony (SOA). Prior to the WM task, negative or neutral emotion was induced using audio clips from the International Affective Digital Sounds (IADS). Pupillometry was simultaneously recorded to provide an objective measure of induced arousal. Self-report measures of early-life stress (i.e., adverse childhood experiences) and current mood states (i.e., depressed mood and anxious feeling) were also collected as covariates. We find that participants initially remember a comparable number of WM items under a short memory-and-mask SOA of 100 ms across emotional conditions, but then encode more items into WM at a longer memory-and-mask SOA of 333 ms under induced negative arousal. These findings suggest that induced negative arousal speeds up WM consolidation. Yet, induced negative arousal does not seem to significantly affect participants’ WM storage capacity estimated from a separate no mask condition. Furthermore, this emotional effect on WM consolidation speed is moderated by key affect-related individual differences. Participants who have greater pupil responses to negative IADS sounds or have more early-life stress show faster WM consolidation under induced negative arousal. Collectively, our findings reveal a critical role of phasic adrenergic responses in the rapid consolidation of visual WM content and the potential moderators of this association.