The fate of monocytes in atherosclerosis.

The fate of monocytes in atherosclerosis.
复制标题

DOI:
10.1111/j.1538-7836.2009.03423.x
复制
发表时间:
2009-07
期刊:
Journal of thrombosis and haemostasis : JTH
影响因子:
--
通讯作者:
Randolph GJ
Randolph GJ
中科院分区:
其他
文献类型:
--
作者:
Randolph GJ

文献摘要

参考文献

被引文献

相似文献

单核细胞是浸润早期动脉粥样硬化斑块的主要炎性细胞类型。它们在斑块中的募集推动了疾病的进展。靶向单核细胞的疾病干预可以在几个点起作用:改变循环单核细胞亚群的表型;减少单核细胞进入斑块的募集;改变单核细胞衍生细胞在动脉粥样硬化中的存活;促进斑块的迁移出口,以解决斑块炎症反应。本文将简要讨论所有这些干预点。
Monocytes are the primary inflammatory cell type that infiltrates early atherosclerotic plaques. Their recruitment into plaques drives disease progression. Disease interventions that target monocytes could act at several points: alteration in the phenotype of circulating monocyte subpopulations; reduced recruitment of monocytes into plaques; alterations in the survival of monocyte-derived cells in atherosclerosis; and promotion of migratory egress from plaques to bring about resolution of the plaque inflammatory response. All of these points of intervention will be briefly discussed in this article.
DOI: 10.1128/mcb.20.11.4106-4114.2000
发表时间: 2000-06-01
影响因子: 5.3
作者:
Jung, S;Aliberti, J;Littman, DR
通讯作者: Littman, DR
DOI: 10.1152/ajpheart.1999.276.4.h1144
发表时间: 1999-04-01
影响因子: 4.8
作者:
Draude, G;Von Hundelshausen, P;Weber, C
通讯作者: Weber, C
DOI: 10.1161/circulationaha.107.745091
发表时间: 2008-04-01
期刊: CIRCULATION
影响因子: 37.8
作者:
Combadiere, Christophe;Potteaux, Stephane;Mallat, Ziad
通讯作者: Mallat, Ziad
DOI: 10.1096/fj.08-112201
发表时间: 2008-10-01
期刊: FASEB JOURNAL
影响因子: 4.8
作者:
Merched, Aksam J.;Ko, Kerry;Chan, Lawrence
通讯作者: Chan, Lawrence
DOI: 10.1172/jci29950
发表时间: 2007-01-01
影响因子: 15.9
作者:
Swirski, Filip K.;Libby, Peter;Pittet, Milkael J.
通讯作者: Pittet, Milkael J.