COMPLETE NUCLEOTIDE-SEQUENCE OF BACTERIOPHAGE MS2-RNA - PRIMARY AND SECONDARY STRUCTURE OF REPLICASE GENE
COMPLETE NUCLEOTIDE-SEQUENCE OF BACTERIOPHAGE MS2-RNA - PRIMARY AND SECONDARY STRUCTURE OF REPLICASE GENE
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DOI：
10.1038/260500a0
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发表时间：
1976-01-01
期刊：
影响因子：
64.8
通讯作者：
YSEBAERT, M
中科院分区：
文献类型：
--
作者：
FIERS, W;CONTRERAS, R;YSEBAERT, M
噬菌体MS2 RNA长3569个核苷酸。确定了第三个也是最后一个基因的核苷酸序列，该基因编码复制酶蛋白。并提出了二级结构模型。生物学特性，如核糖体结合和密码子相互作用，现在可以在分子基础上讨论。由于该RNA的其他区域的序列已经公布，现在已经建立了病毒基因组的完整的主要化学结构。
Bacteriophage MS2 RNA is 3569 nucleotides long. The nucleotide sequence was established for the 3rd and last gene, which codes for the replicase protein. A secondary structure model was also proposed. Biological properties, such as ribosome binding and codon interactions, can now be discussed on a molecular basis. As the sequences for the other regions of this RNA were already published, the complete, primary chemical structure of a viral genome is now established.